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光学血糖无创检测及其研究进展。

Optical blood glucose non-invasive detection and its research progress.

机构信息

College of Mechanical and Electronic Engineering, Pingxiang University, Pingxiang 330073, P.R. China.

Big Data and Internet of Things School, Chongqing Vocational Institute of Engineering, Chongqing 402260, China.

出版信息

Analyst. 2024 Sep 23;149(19):4830-4841. doi: 10.1039/d4an01048e.

Abstract

Blood glucose concentration is an important index for the diagnosis of diabetes, its self-monitoring technology is the method for scientific diabetes management. Currently, the typical household blood glucose meters have achieved great success in diabetes management, but they are discrete detection methods, and involve invasive blood sampling procedures. Optical detection technologies, which use the physical properties of light to detect the glucose concentration in body fluids non-invasively, have shown great potential in non-invasive blood glucose detection. This article summarized and analyzed the basic principles, research status, existing problems, and application prospects of different optical glucose detection technologies. In addition, this article also discusses the problems of optical detection technology in wearable sensors and perspectives on the future of non-invasive blood glucose detection technology to improve blood glucose monitoring in diabetic patients.

摘要

血糖浓度是诊断糖尿病的重要指标,其自我监测技术是科学管理糖尿病的方法。目前,典型的家用血糖仪在糖尿病管理方面已取得巨大成功,但它们是离散的检测方法,且涉及到有创的血液采样过程。光学检测技术利用光的物理特性非侵入式地检测体液中的葡萄糖浓度,在无创血糖检测方面显示出巨大的潜力。本文总结和分析了不同光学葡萄糖检测技术的基本原理、研究现状、存在的问题和应用前景。此外,本文还讨论了光学检测技术在可穿戴传感器中的问题以及对无创血糖检测技术未来的展望,以改善糖尿病患者的血糖监测。

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