Gao Xinyu, Xu Zekai, Chen Liqun
Academy of Medical Engineering and Translational Medicine, TianJin University, TianJin 300072, P.R.China.
Department of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, TianJin 300072, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Apr 25;40(2):365-372. doi: 10.7507/1001-5515.202202017.
Blood glucose monitoring has become the weakest point in the overall management of diabetes in China. Long-term monitoring of blood glucose levels in diabetic patients has become an important means of controlling the development of diabetes and its complications, so that technological innovations in blood glucose testing methods have far-reaching implications for accurate blood glucose testing. This article discusses the basic principles of minimally invasive and non-invasive blood glucose testing assays, including urine glucose assays, tear assays, methods of extravasation of tissue fluid, and optical detection methods, etc., focuses on the advantages of minimally invasive and non-invasive blood glucose testing methods and the latest relevant results, and summarizes the current problems of various testing methods and prospects for future development trends.
血糖监测已成为中国糖尿病整体管理中的薄弱环节。对糖尿病患者进行长期血糖水平监测已成为控制糖尿病及其并发症发展的重要手段，因此血糖检测方法的技术创新对于准确检测血糖具有深远意义。本文讨论了微创和无创血糖检测方法的基本原理，包括尿糖检测、泪液检测、组织液渗出法以及光学检测方法等，重点介绍了微创和无创血糖检测方法的优势及最新相关成果，并总结了各种检测方法目前存在的问题以及未来发展趋势的展望。
