Levin Mark D
Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Synlett. 2024 Aug;35(13):1471-1474. doi: 10.1055/s-0043-1763623. Epub 2023 Nov 9.
Retrosynthetic simplicity is introduced as a metric by which methods can be evaluated. An argument in favor of reactions which are retrosynthetically simple is put forward, and recent examples in the context of skeletal editing from my own laboratory as well as contributions from others are analyzed critically through this lens.
逆合成简单性被引入作为一种评估方法的指标。提出了支持逆合成简单反应的观点,并通过这一视角对我自己实验室在骨架编辑方面的近期实例以及其他研究人员的贡献进行了批判性分析。