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基于高效计算方法的冠状病毒模型随机时滞分析。

Stochastic delayed analysis of coronavirus model through efficient computational method.

机构信息

Department of Mathematics and Statistics, The University of Lahore, Lahore, Pakistan.

Department of Physical Sciences, The University of Chenab, Gujrat, Pakistan.

出版信息

Sci Rep. 2024 Sep 10;14(1):21170. doi: 10.1038/s41598-024-70089-z.

DOI:10.1038/s41598-024-70089-z
PMID:39256433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11387501/
Abstract

Stochastic delayed modeling has a significant non-pharmaceutical intervention to control transmission dynamics of infectious diseases and its results are close to the reality of nature. The covid-19 has been controlled globally but there is still a threat and appears in different variants like omicron and SARS-CoV-2 etc. globally. This article, considered pattern a mathematical model based on Susceptible, Infected, and recovered populations with highly nonlinear incidence rates. we studied the dynamics of the coronavirus model; a newly proposed version is a stochastic delayed model that is based on nonlinear stochastic delayed differential equations (SDDEs). Transition probabilities and parametric perturbation methods were used for the construction of the stochastic delayed model. The fundamental properties like positivity, boundedness, existence and uniqueness, and stability results of equilibria of the model with certain conditions of reproduction number are studied regularly. Also, the extinction and persistence of disease are studied with the help of well-known theorems. The numerical methods used to find a visualization of results due to the complexity of stochastic delayed differential equations. Furthermore, for computational analysis, we implemented existing methods in the literature and compared their results with the proposed method like nonstandard finite difference for stochastic delayed model. The proposed method restores all dynamical properties of the model with a free choice of time steps.

摘要

随机时滞建模对控制传染病的传播动力学具有重要的非药物干预作用,其结果更接近自然的现实。虽然全球已经控制住了新冠疫情,但它仍然存在威胁,并以不同的变体(如奥密克戎和 SARS-CoV-2 等)在全球范围内出现。本文考虑了一种基于易感者、感染者和恢复者群体的数学模型,该模型具有高度非线性的发病率。我们研究了冠状病毒模型的动力学;一个新提出的版本是基于非线性随机时滞微分方程(SDDEs)的随机时滞模型。我们使用转移概率和参数摄动方法来构建随机时滞模型。在一定繁殖数条件下,对模型的正定性、有界性、存在性和唯一性以及平衡点稳定性结果进行了研究。此外,还借助著名的定理研究了疾病的灭绝和持续存在。由于随机时滞微分方程的复杂性,我们使用数值方法来可视化结果。此外,为了进行计算分析,我们实现了文献中现有的方法,并将其结果与所提出的方法(如随机延迟模型的非标准有限差分)进行了比较。该方法可以在自由选择时间步长的情况下恢复模型的所有动力学特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/2bf687399a3c/41598_2024_70089_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/e765b2522a41/41598_2024_70089_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/f2e46fa849d4/41598_2024_70089_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/49696dd64ae6/41598_2024_70089_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/2bf687399a3c/41598_2024_70089_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/e765b2522a41/41598_2024_70089_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/f2e46fa849d4/41598_2024_70089_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/49696dd64ae6/41598_2024_70089_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f8/11387501/2bf687399a3c/41598_2024_70089_Fig4_HTML.jpg

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本文引用的文献

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Dynamics of a Fractional-Order Delayed Model of COVID-19 with Vaccination Efficacy.具有疫苗接种效果的COVID-19分数阶延迟模型的动力学
Vaccines (Basel). 2023 Mar 29;11(4):758. doi: 10.3390/vaccines11040758.
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Remote learning during COVID-19: cognitive appraisals and perceptions of english medium of instruction (EMI) students.新冠疫情期间的远程学习:以英语为教学语言(EMI)的学生的认知评估与看法
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Emergency remote teaching during the COVID-19 pandemic: Parents experiences and perspectives.
新冠疫情期间的应急远程教学:家长的经历与观点
Educ Inf Technol (Dordr). 2021;26(6):6699-6718. doi: 10.1007/s10639-021-10520-4. Epub 2021 Mar 29.
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Analysis of the stochastic model for predicting the novel coronavirus disease.新型冠状病毒病预测的随机模型分析
Adv Differ Equ. 2020;2020(1):568. doi: 10.1186/s13662-020-03025-w. Epub 2020 Oct 8.
5
Stochastic SIRC epidemic model with time-delay for COVID-19.用于新冠肺炎的具有时滞的随机SIRC流行病模型。
Adv Differ Equ. 2020;2020(1):502. doi: 10.1186/s13662-020-02964-8. Epub 2020 Sep 18.
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Adv Differ Equ. 2020;2020(1):373. doi: 10.1186/s13662-020-02834-3. Epub 2020 Jul 22.
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Study of transmission dynamics of novel COVID-19 by using mathematical model.运用数学模型对新型冠状病毒肺炎传播动力学的研究
Adv Differ Equ. 2020;2020(1):323. doi: 10.1186/s13662-020-02783-x. Epub 2020 Jul 1.
8
Statistical analysis of forecasting COVID-19 for upcoming month in Pakistan.巴基斯坦未来一个月新冠疫情预测的统计分析。
Chaos Solitons Fractals. 2020 Sep;138:109926. doi: 10.1016/j.chaos.2020.109926. Epub 2020 May 25.
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