• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

暴发性猪链球菌感染导致心肌损伤和中毒性休克样综合征：一例报告

Fulminant Streptococcus suis Infection Causing Myocardial Damage and Toxic Shock-Like Syndrome: A Case Report.

作者信息

Hayasaka Taiki, Ono Toshiyuki, Takeuchi Toshiharu, Sato Ayaka, Kikuchi Yuta, Kinebuchi Takahiro, Tanino Mishie, Okada Motoi, Nakagawa Naoki

机构信息

Division of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, JPN.

Department of Emergency Medicine, Asahikawa Medical University, Asahikawa, JPN.

出版信息

Cureus. 2024 Aug 11;16(8):e66625. doi: 10.7759/cureus.66625. eCollection 2024 Aug.

DOI:10.7759/cureus.66625
PMID:39258080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11386272/
Abstract

There have been no prior reports of direct myocardial damage caused by , and understanding the clinical course of myocardial involvement is crucial for early diagnosis and initiation of treatment for this infection. A male pig farmer presented as an outpatient with a fever and sore throat, but within hours, his cardiac function declined, and his general condition deteriorated. Despite receiving comprehensive treatment, he succumbed to complications associated with toxic shock-like syndrome (TSLS). Blood cultures identified , and myocardial pathology revealed the presence of this bacterium in necrotic areas. This case marks the first reported instance of myocardial damage accompanied by TSLS due to , highlighting the significance of this infection.

摘要

此前尚无关于[病原体名称]引起直接心肌损伤的报道，了解心肌受累的临床过程对于该感染的早期诊断和治疗启动至关重要。一名男性养猪户门诊就诊时出现发热和咽痛，但数小时内心脏功能下降，全身状况恶化。尽管接受了综合治疗，他仍死于与中毒性休克样综合征（TSLS）相关的并发症。血培养鉴定出[病原体名称]，心肌病理学显示坏死区域存在这种细菌。该病例是首例报道的因[病原体名称]导致伴有TSLS的心肌损伤，凸显了这种感染的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/dfe810485c93/cureus-0016-00000066625-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/7ab4330e98d2/cureus-0016-00000066625-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/15af63e4990c/cureus-0016-00000066625-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/47890a5c1f06/cureus-0016-00000066625-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/dfe810485c93/cureus-0016-00000066625-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/7ab4330e98d2/cureus-0016-00000066625-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/15af63e4990c/cureus-0016-00000066625-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/47890a5c1f06/cureus-0016-00000066625-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e8/11386272/dfe810485c93/cureus-0016-00000066625-i04.jpg

相似文献

1
Fulminant Streptococcus suis Infection Causing Myocardial Damage and Toxic Shock-Like Syndrome: A Case Report.暴发性猪链球菌感染导致心肌损伤和中毒性休克样综合征：一例报告
Cureus. 2024 Aug 11;16(8):e66625. doi: 10.7759/cureus.66625. eCollection 2024 Aug.
2
[Streptococcal Toxic Shock-like Syndrome due to Streptococcus suis Serotype 2 in a Japanese Pig Farmer].一名日本养猪农民感染猪链球菌2型所致的链球菌中毒性休克样综合征
Kansenshogaku Zasshi. 2015 Nov;89(6):741-4. doi: 10.11150/kansenshogakuzasshi.89.741.
3
Streptococcus suis: a re-emerging pathogen associated with occupational exposure to pigs or pork products. Part I - Epidemiology.猪链球菌：一种与职业性接触猪或猪肉产品相关的再度出现的病原体。第一部分 - 流行病学
Ann Agric Environ Med. 2017 Dec 23;24(4):683-695. doi: 10.26444/aaem/79813. Epub 2017 Nov 29.
4
Targeting TREM-1 Signaling in the Presence of Antibiotics is Effective Against Streptococcal Toxic-Shock-Like Syndrome (STSLS) Caused by Streptococcus suis.在使用抗生素的情况下靶向触发受体表达上调分子-1（TREM-1）信号传导可有效对抗猪链球菌引起的链球菌中毒性休克样综合征（STSLS）。
Front Cell Infect Microbiol. 2015 Nov 12;5:79. doi: 10.3389/fcimb.2015.00079. eCollection 2015.
5
Streptococcus suis toxic-shock syndrome and meningitis.猪链球菌中毒性休克综合征和脑膜炎
J Med Assoc Thai. 1997 Jan;80(1):63-8.
6
TRIM32 Drives Pathogenesis in Streptococcal Toxic Shock-Like Syndrome and Streptococcus suis Meningitis by Regulating Innate Immune Responses.TRIM32 通过调节固有免疫反应驱动链球菌中毒性休克样综合征和猪链球菌脑膜炎的发病机制。
Infect Immun. 2020 Mar 23;88(4). doi: 10.1128/IAI.00957-19.
7
Case report: One human Streptococcus suis occurred in Shandong Province, China.病例报告：中国山东省出现 1 例人类感染猪链球菌病例。
Medicine (Baltimore). 2022 Dec 23;101(51):e32414. doi: 10.1097/MD.0000000000032414.
8
[Streptococcus suis infection--clinical manifestations].[猪链球菌感染——临床表现]
Med Pregl. 2005 May-Jun;58(5-6):236-9. doi: 10.2298/mpns0506236d.
9
Streptococcus suis-related prosthetic joint infection and streptococcal toxic shock-like syndrome in a pig farmer in the United States.美国一名养猪农民感染猪链球菌相关人工关节感染及链球菌中毒性休克样综合征
J Clin Microbiol. 2014 Jun;52(6):2254-8. doi: 10.1128/JCM.02934-13. Epub 2014 Apr 9.
10
A Case of Life-Threating Infection Presented as Septic Shock and Multiple Abscesses.一例以感染性休克和多发性脓肿形式出现的危及生命的感染病例。
Infect Chemother. 2018 Sep;50(3):274-279. doi: 10.3947/ic.2018.50.3.274.

引用本文的文献

1
: Epidemiology and resistance evolution of an emerging zoonotic bacteria.一种新兴人畜共患病细菌的流行病学与耐药性演变
One Health. 2025 Jun 16;21:101098. doi: 10.1016/j.onehlt.2025.101098. eCollection 2025 Dec.

本文引用的文献

1
Multiple Drug Resistant Strains-An Actual Problem in Pig Farms in Western Romania.多重耐药菌株——罗马尼亚西部养猪场的一个实际问题。
Antibiotics (Basel). 2024 Mar 19;13(3):277. doi: 10.3390/antibiotics13030277.
2
subtilisin-like serine proteases SspA-1 and SspA-2 interplay with complement C3a and C5a to facilitate bacterial immune evasion and infection.枯草溶菌素样丝氨酸蛋白酶 SspA-1 和 SspA-2 与补体 C3a 和 C5a 相互作用，以促进细菌的免疫逃避和感染。
Virulence. 2024 Dec;15(1):2301246. doi: 10.1080/21505594.2023.2301246. Epub 2024 Jan 16.
3
The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs.
人畜共患病原体从集约化养殖猪的微生物群中出现和多样化。
Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2307773120. doi: 10.1073/pnas.2307773120. Epub 2023 Nov 14.
4
outbreak caused by an emerging zoonotic strain with acquired multi-drug resistance in Thailand.在泰国暴发的由新出现的人畜共患病株引起的、具有获得性多重耐药性的疫情。
Microb Genom. 2023 Feb;9(2). doi: 10.1099/mgen.0.000952.
5
Update on Research and Prevention in the Era of Antimicrobial Restriction: 4th International Workshop on .抗菌药物限制时代的研究与预防最新进展：第四届国际研讨会
Pathogens. 2020 May 14;9(5):374. doi: 10.3390/pathogens9050374.
6
Clinical Manifestations and Risk Factors of Mortality Among Northern Thai Population: Retrospective 13-Year Cohort Study.泰国北部人群死亡率的临床表现及危险因素：13年回顾性队列研究
Infect Drug Resist. 2019 Dec 30;12:3955-3965. doi: 10.2147/IDR.S233326. eCollection 2019.
7
Risk factors for Streptococcus suis infection: A systematic review and meta-analysis.猪链球菌感染的危险因素：系统评价和荟萃分析。
Sci Rep. 2018 Sep 6;8(1):13358. doi: 10.1038/s41598-018-31598-w.
8
A Streptococcus suis Live Vaccine Suppresses Streptococcal Toxic Shock-Like Syndrome and Provides Sequence Type-Independent Protection.猪链球菌活疫苗抑制链球菌中毒性休克样综合征并提供与序列型无关的保护。
J Infect Dis. 2019 Jan 9;219(3):448-458. doi: 10.1093/infdis/jiy512.
9
Streptococcus suis vaccines: candidate antigens and progress.猪链球菌疫苗：候选抗原及研究进展
Expert Rev Vaccines. 2015;14(12):1587-608. doi: 10.1586/14760584.2015.1101349. Epub 2015 Oct 15.
10
Streptococcus suis infection in hospitalized patients, Nakhon Phanom Province, Thailand.泰国那空拍侬府住院患者中的猪链球菌感染
Emerg Infect Dis. 2015 Feb;21(2):345-8. doi: 10.3201/eid2102.140961.