Cost K M, West C S, Brinson D, Polk H C
J Immunoassay. 1985;6(1-2):23-43. doi: 10.1080/01971528508063019.
Using an ELISA technique, specific IgG and specific IgM antibodies to several strains of Escherichia coli and Pseudomonas aeruginosa were measured in 100 normal adults. The distribution of antibody activity to E. coli was narrow, with mean values less than 0.50 OD units. The one exception was in IgG activity to E. coli O.. Mean values for activity against P. aeruginosa ranged from 0.35 to 0.79 OD units. Significant rank order correlations were found for IgM activity among all E. coli and P. aeruginosa strains. The correlations were less consistent for the IgG activity. This baseline data will be used to monitor antibody activity to these common microbes along with several other parameters in a group of ill surgical patients.
采用酶联免疫吸附测定（ELISA）技术，对100名正常成年人检测了针对几种大肠杆菌和铜绿假单胞菌菌株的特异性IgG和特异性IgM抗体。针对大肠杆菌的抗体活性分布范围较窄，平均值低于0.50光密度（OD）单位。唯一的例外是针对大肠杆菌O157:H7的IgG活性。针对铜绿假单胞菌的活性平均值在0.35至0.79 OD单位之间。在所有大肠杆菌和铜绿假单胞菌菌株中，发现IgM活性存在显著的等级顺序相关性。IgG活性的相关性则不太一致。这些基线数据将用于监测一组外科疾病患者针对这些常见微生物的抗体活性以及其他几个参数。
