Mandujano-Hernández Antonio, Martínez-Vázquez Ana Verónica, Paz-González Alma D, Herrera-Mayorga Verónica, Sánchez-Sánchez Mario, Lara-Ramírez Edgar E, Vázquez Karina, de Jesús de Luna-Santillana Erick, Bocanegra-García Virgilio, Rivera Gildardo
Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Unidad Académica Multidisciplinaria Mante, Universidad Autónoma de Tamaulipas, Mante 89840, Mexico.
Animals (Basel). 2024 Aug 27;14(17):2490. doi: 10.3390/ani14172490.
β-lactam antibiotics are a key element in the treatment of bacterial infections. However, the excessive use of these antibiotics has contributed to the emergence of β-lactam-resistant enterobacteria, including . One of the main challenges facing the public health sector is antibacterial resistance (ABR), mainly due to limited options in its pharmacological treatment. Currently, extended-spectrum β-lactamases (ESBLs) present an alarming situation, as there is an increase in morbidity and mortality rates, prolonged hospital stays, and increased costs for sanitary supplies, which involve not only humans but also the environment and animals, especially animals destined for food production. This review presents an analysis of the prevalence of ESBL-producing and its distribution in different animal sources throughout the world, providing an understanding of the association with resistance and virulence genes, as well as perceiving the population structure of .
β-内酰胺类抗生素是治疗细菌感染的关键要素。然而，这些抗生素的过度使用导致了产β-内酰胺酶肠杆菌的出现，包括……。公共卫生部门面临的主要挑战之一是抗菌药物耐药性（ABR），主要原因是其药物治疗选择有限。目前，超广谱β-内酰胺酶（ESBLs）呈现出令人担忧的局面，因为发病率和死亡率上升、住院时间延长以及卫生用品成本增加，这不仅涉及人类，还涉及环境和动物，尤其是用于食品生产的动物。本综述分析了产ESBLs的……在世界各地不同动物来源中的流行情况及其分布，有助于了解其与耐药基因和毒力基因的关联，以及认识……的种群结构。
