Division of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Division of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Addict Behav. 2025 Jan;160:108162. doi: 10.1016/j.addbeh.2024.108162. Epub 2024 Sep 12.
Substance use in youth remains a pressing problem in the United States. Existing studies have shown the importance of neuropathways responsible for affective response and reward motivation in adolescents' substance use initiation and maintenance. However, limited observational studies have explored the relationship between aspects of behavioral motivation traits and the likelihood of substance use initiation in adolescents. In this prospective cohort study, we assessed the associations between behavioral motivation traits based on the Behavioral Inhibition and Approach Systems (BIS-BAS) Scale and substance use initiation using data from the Adolescent Brain Cognitive Development (ABCD) study.
In the 9216 eligible sample population, we assessed the associations between mean Behavioral Inhibition System (BIS) / Behavioral Approach System (BAS) scores measured at year 2 of the ABCD study and substance use initiation at year 3 of the ABCD study using multivariable logistic regressions adjusting for ABCD study site, sampling weights, as well as sociodemographic characteristics.
We found that higher BIS mean score was associated with higher odds of initiating substance use at year 3 (AOR=1.20, 95 % CI: 1.03, 1.40). Out of three BAS measure categories, only BAS Fun-seeking mean score was positively associated with higher odds of initiating substance use at year 3 (AOR=1.23, 95 % CI: 1.07, 1.43).
Our study showed that inhibitory and fun-seeking behavioral tendencies are associated with an increased likelihood of substance use initiation in adolescents. Our findings suggest a potential pathway linking emotional traits to early substance initiation in adolescents.
在美国，青少年的物质使用仍然是一个紧迫的问题。现有研究表明，负责情感反应和奖励动机的神经通路在青少年物质使用的开始和维持中起着重要作用。然而，有限的观察性研究探讨了行为动机特征的各个方面与青少年物质使用开始的可能性之间的关系。在这项前瞻性队列研究中，我们根据行为抑制和趋近系统（BIS-BAS）量表评估了行为动机特征与青少年物质使用开始之间的关联，使用来自青少年大脑认知发展（ABCD）研究的数据。
在符合条件的 9216 名样本人群中，我们使用 ABCD 研究第 2 年测量的平均行为抑制系统（BIS）/行为趋近系统（BAS）评分和 ABCD 研究第 3 年物质使用开始的多变量逻辑回归评估了两者之间的关联，调整了 ABCD 研究地点、抽样权重以及社会人口统计学特征。
我们发现，较高的 BIS 平均得分与第 3 年开始物质使用的几率较高相关（AOR=1.20，95%CI：1.03，1.40）。在三个 BAS 测量类别中，只有寻求乐趣的 BAS 平均得分与第 3 年开始物质使用的几率较高呈正相关（AOR=1.23，95%CI：1.07，1.43）。
我们的研究表明，抑制和寻求乐趣的行为倾向与青少年物质使用开始的可能性增加有关。我们的研究结果表明，情绪特征与青少年早期物质使用开始之间存在潜在的联系。
