Sawada T, Rimler R B, Rhoades K R
Am J Vet Res. 1985 Jun;46(6):1247-50.
Antibodies against Pasteurella multocida capsular types B and E, which cause hemorrhagic septicemia, were demonstrated in a high percentage of sera from domestic feeder calves. Since the calves had not been vaccinated with any Pasteurella organisms, the antibodies were considered to be naturally acquired. The antibodies were demonstrated by passively immunizing mice and by indirect hemagglutination and agglutination tests. Sera from 81% (44 of 54) of the calves protected mice that were challenge exposed with a capsular type B organism, and sera from 91% (49 of 54) of the calves protected mice that were challenge exposed with a capsular type E organism. Indirect hemagglutination and agglutination tests demonstrated antibody in nearly all sera. Since capsular type E organisms have been isolated only in Africa and there is only 1 report of capsular type B isolation from cattle in the United States, these organisms were not considered likely sources of the antigenic stimulation that provoked production of these antibodies.
在家养育肥牛犊的血清中，有很大比例检测出了针对多杀性巴氏杆菌B型和E型荚膜的抗体，这两种荚膜会引发出血性败血症。由于这些牛犊未接种过任何巴氏杆菌菌株，所以这些抗体被认为是自然获得的。通过对小鼠进行被动免疫以及间接血凝试验和凝集试验，证实了这些抗体的存在。81%（54头中的44头）牛犊的血清能保护经B型荚膜菌株攻击的小鼠，91%（54头中的49头）牛犊的血清能保护经E型荚膜菌株攻击的小鼠。间接血凝试验和凝集试验在几乎所有血清中都检测到了抗体。由于E型荚膜菌株仅在非洲被分离出来，而在美国仅有1例从牛身上分离出B型荚膜菌株的报告，所以这些菌株不太可能是引发这些抗体产生的抗原刺激源。
