Indiastari Dewi, Fajar Jonny K, Tamara Fredo, Runesi Odis, Hakim Lukman N, Chotimah Kusnul, Rahmani Alinda, Saputro Teguh D, Afrilla Dian, Firmansyah Ervin, Dau Daniel, Dzhyvak Volodymyr
Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Narra J. 2024 Aug;4(2):e866. doi: 10.52225/narra.v4i2.866. Epub 2024 Jul 17.
Assessing the acceptance of the monkeypox vaccine is crucial for the success of vaccination programs, yet the prevalence reports remain inconclusive. The aim of this study was to determine the global prevalence of monkeypox vaccine acceptance and identify its associated factors. A meta-analysis was conducted with a comprehensive search strategy on the following databases, including Scopus, Embase, and PubMed, for articles published up to April 5, 2024. This study utilizes a single-arm meta-analysis to calculate the pooled prevalence of monkeypox vaccine acceptance. A -test was employed to identify factors associated with the vaccine acceptance. Our study analyzed 51 articles encompassing 98,746 participants, revealing an overall monkeypox vaccine acceptance rate of 65%. Notably, the highest acceptance rates were observed among men who have sex with men (MSMs), while healthcare workers (HCWs) showed the lowest acceptance rates. Additionally, our findings indicated an increased acceptance in individuals with educational attainment beyond a bachelor's degree, a history of COVID-19 and influenza vaccination, homosexual orientation, and HIV-positive status. Conversely, lower acceptance risk was associated with those with educational attainment below a bachelor's degree, heterosexual orientation, and bisexual orientation. In conclusion, our current study has determined the rate of monkeypox vaccine acceptance and identified its associated factors. These findings offer valuable insights as the foundation for targeted policies to manage and increase acceptance rates.
评估猴痘疫苗的接受度对于疫苗接种计划的成功至关重要，但患病率报告仍无定论。本研究的目的是确定全球猴痘疫苗接受度的患病率，并确定其相关因素。采用综合检索策略对包括Scopus、Embase和PubMed在内的以下数据库进行荟萃分析，以查找截至2024年4月5日发表的文章。本研究采用单臂荟萃分析来计算猴痘疫苗接受度的合并患病率。采用A检验来确定与疫苗接受度相关的因素。我们的研究分析了51篇文章，涵盖98746名参与者，显示猴痘疫苗总体接受率为65%。值得注意的是，男男性行为者（MSM）的接受率最高，而医护人员（HCW）的接受率最低。此外，我们的研究结果表明，拥有学士学位以上学历、有新冠病毒病和流感疫苗接种史、同性恋取向以及艾滋病毒呈阳性的个体接受度有所提高。相反，接受风险较低与学士学位以下学历、异性恋取向和双性恋取向的人有关。总之，我们目前的研究确定了猴痘疫苗的接受率，并确定了其相关因素。这些发现为制定有针对性的政策以管理和提高接受率提供了宝贵的见解。
