Al Shubbar Mohammed D, Bojabara Loay M, Al Qunais Abdulaziz A, Huldar Ammar S, Alamro Saud, Alameer Mohammed H, Alameer Faris H
College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Cureus. 2024 Aug 14;16(8):e66842. doi: 10.7759/cureus.66842. eCollection 2024 Aug.
This narrative review meticulously examines the intricate landscape of poisoning incidents within Saudi Arabia, delineating the prevalence and characteristics across three main categories: pharmaceutical, illicit, and chemical substances. Pharmaceutical agents, particularly analgesics and antipsychotics, are identified as leading causes of acute adult poisoning, highlighting the paramount role of their widespread accessibility and the potential risks associated with over-the-counter availability. The review underscores the alarming prevalence of over-the-counter analgesics, such as paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs), as the most frequent culprits in poisoning cases, with a significant correlation observed between analgesic poisoning and gender, notably affecting the female population. Additionally, the study delves into the burgeoning issue of illicit drug use, with opioids and amphetamines emerging as substantial contributors to the poisoning landscape, reflecting a broader global trend of increasing substance misuse and its associated health risks. Chemical poisoning, encompassing a range of substances from household cleaners to industrial chemicals, presents another critical area of concern, with specific emphasis on the dangers posed by antiseptics, detergents, and organophosphates. The review identifies a pressing need for targeted public health interventions and policy reforms aimed at mitigating the risks associated with these diverse types of poisoning. By offering a comprehensive overview of the poisoning epidemiology in Saudi Arabia, the study contributes valuable insights into the multifaceted nature of this public health challenge, advocating for enhanced regulatory measures, public awareness campaigns, and improved access to mental health services to address the underlying factors contributing to poisoning incidents.
这篇叙述性综述精心审视了沙特阿拉伯中毒事件的复杂情况,描绘了药物、非法和化学物质这三大类中毒事件的发生率及特征。药物制剂,尤其是镇痛药和抗精神病药,被确定为成人急性中毒的主要原因,凸显了其广泛可得性以及非处方可得性所带来的潜在风险的重要作用。该综述强调,非处方镇痛药,如对乙酰氨基酚和非甾体抗炎药(NSAIDs),在中毒病例中最为常见,是罪魁祸首,且镇痛药中毒与性别之间存在显著关联,尤其对女性人群影响较大。此外,该研究深入探讨了非法药物使用这一日益严重的问题,阿片类药物和苯丙胺类药物成为中毒情况的重要促成因素,反映了全球范围内物质滥用增加及其相关健康风险的更广泛趋势。化学中毒涵盖从家用清洁剂到工业化学品等一系列物质,是另一个关键的关注领域,特别强调了防腐剂、洗涤剂和有机磷化合物所带来的危险。该综述指出迫切需要有针对性的公共卫生干预措施和政策改革,以降低与这些不同类型中毒相关的风险。通过全面概述沙特阿拉伯的中毒流行病学情况,该研究为这一公共卫生挑战的多方面性质提供了宝贵见解,倡导加强监管措施、开展公众意识宣传活动以及改善心理健康服务的可及性,以解决导致中毒事件的潜在因素。