Poisoning-related emergency department visits: the experience of a Saudi high-volume toxicology center.

BACKGROUND

Acute poisoning is a major contributing factor to mortality and morbidity. There is a lack of research on the epidemiology of acute poisoning risk factors in Saudi Arabia.

OBJECTIVES

Descriptive overview of poisoning cases at a tertiary care center.

DESIGN

Descriptive, medical record review.

SETTINGS

Tertiary care center in Riyadh.

PATIENTS AND METHODS

From the electronic medical record system, we collected demographic information, medical history, and the poisoning history on all emergency department visits diagnosed as acute poisoning from January 2016 to January 2021. Patients were classed as children (<18 years old) or adults, and further classified by body mass index.

MAIN OUTCOME MEASURES

Intensive care unit (ICU) admission, organ transplantation, and mortality were classified as poor outcomes.

SAMPLE SIZE

492 adults and 1013 children (<18 years old) were identified.

RESULTS

The most frequent agent in poisoning for both groups was acetaminophen (n=52, 10.57% and n=100, 9.87%, respectively). The ICU admission rate was 6.7% and 4.8%, and the mortality rate 0.8% and 0.3%, respectively. The accidental poisoning rate was 57.7% among adults (n=284) and 67.6% among children (n=658). The suicide intention rate was 11.2% (n=55) and 7.4% (n=75) among adults and children, respectively. The management for both populations was nonspecific, involving observation, supportive measures, and symptomatic treatment.

CONCLUSION

Although the ICU admission rates were consistent with reported data, the mortality rate was marginally lower. The pediatric predominance in the population implies a lack of caregiver education in the region regarding the safe storage of drugs and household products, as well as the use of child-resistant packaging. The high rate of accidental poisoning in both age groups should prompt further investment to promote public health education on the rational use and safe storage of toxic agents and self-protection. The high suicide intention rate needs to be investigated to develop multidisciplinary risk prevention strategies.

LIMITATIONS

Single center, retrospective, small population size.

CONFLICT OF INTEREST

None.