Iyer Murali Naresh Vishwanath, Mohammed Awais Ilyas, Gelli Sumathi, Gejjalagere Chandrashekar Nishanth, Ramanathan Nitin, Jain Rishabh, Lohakare Tejaswee
General Medicine, United Lincolnshire Hospitals NHS Trust, Grantham, GBR.
Internal Medicine, Bharat Ratna Dr. B.R. Ambedkar Medical College, Bangalore, IND.
Cureus. 2024 Aug 14;16(8):e66849. doi: 10.7759/cureus.66849. eCollection 2024 Aug.
Background The term "cardiomyopathy" encompasses a wide range of diseases with various underlying causes. Dilated cardiomyopathy (DCM) is characterized by ventricular dilation and impaired cardiac function in the absence of congenital, valvular, hypertensive, or ischemic heart disease (IHD). This study was motivated by the high prevalence of underlying DCM and chronic heart failure, coupled with a lack of comprehensive information on DCM. The primary objective of this study was to identify the clinical characteristics and contributing factors associated with individuals diagnosed with DCM. Methods A total of 120 patients with DCM were enrolled in a two-year, hospital-based observational cross-sectional study conducted within the Medicine Department of a tertiary care center. The study assessed risk factors, including IHD, diabetes mellitus, alcohol consumption, and smoking. Results DCM was observed across all age groups, though it was notably more prevalent among middle-aged individuals (n = 50, or 41.7%) and the elderly (n = 35, or 37.5%). The condition was more commonly seen in men. IHD emerged as the predominant risk factor, affecting 75% of patients (n = 90), followed by diabetes mellitus (n = 85, or 70.8%), alcohol use (n = 75, or 62.5%), and smoking (n = 50, or 41.7%). Common symptoms included pedal edema, palpitations, easy fatigability, and exertional dyspnea. Conclusion In conclusion, DCM is a critical condition that necessitates vigilant monitoring. Consistent observation of symptoms, recognition of potential triggers, and prompt identification of adverse drug reactions, electrolyte disturbances, and echocardiographic changes are essential. This awareness and early detection were responsible for the lower mortality and early symptom improvement observed in the present study group.
背景 “心肌病” 一词涵盖了多种病因各异的疾病。扩张型心肌病(DCM)的特征是心室扩张且在无先天性、瓣膜性、高血压性或缺血性心脏病(IHD)的情况下心脏功能受损。本研究的起因是潜在DCM和慢性心力衰竭的高患病率,以及缺乏关于DCM的全面信息。本研究的主要目的是确定与诊断为DCM的个体相关的临床特征和促成因素。方法 共有120例DCM患者参加了一项在三级医疗中心内科进行的为期两年的基于医院的观察性横断面研究。该研究评估了包括IHD、糖尿病、饮酒和吸烟在内的风险因素。结果 在所有年龄组中均观察到DCM,不过在中年个体(n = 50,占41.7%)和老年人(n = 35,占37.5%)中更为普遍。该疾病在男性中更常见。IHD是主要的风险因素,影响了75%的患者(n = 90),其次是糖尿病(n = 85,占70.8%)、饮酒(n = 75,占62.5%)和吸烟(n = 50,占41.7%)。常见症状包括足部水肿、心悸、易疲劳和劳力性呼吸困难。结论 总之,DCM是一种需要密切监测的严重疾病。持续观察症状、识别潜在诱因以及及时识别不良药物反应、电解质紊乱和超声心动图变化至关重要。这种意识和早期发现是本研究组死亡率较低和症状早期改善的原因。