Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Indian J Dent Res. 2024 Apr 1;35(2):232-238. doi: 10.4103/ijdr.ijdr_761_23. Epub 2024 Sep 14.
Dental implants are used in dentistry to replace teeth, restore function and improve the quality of life for patients. Osseointegration is critical for the success of dental implants. Implant surface modification can enhance osseointegration. Gold nanoparticles have emerged as a promising coating material for dental implants owing to their unique physicochemical properties. We aimed to review published literature to assess the effect of gold nanoparticle coating in increasing osseointegration of dental implants.
A database search yielded a total of 14 articles between January 2011 till December 2021, of which nine articles were excluded and five studies met the inclusion criteria. All studies reported improved osseointegration outcomes with gold nanoparticle coating compared to uncoated controls.
The most reported osseointegration outcomes were bone-implant contact, removal torque (RTQ) and histological analysis of bone formation around the implant. Mean RTQ values for coated implants ranged from 6.7 to 52.8 Ncm, compared to 3.7-40.8 Ncm for uncoated controls. The histological analysis showed greater bone formation and density around the coated implants compared to uncoated implants. Gold nanoparticle coating appears to have a positive effect on osseointegration. The results of included studies suggest that gold nanoparticle-coated implants promote greater bone-implant contact (BIC), RTQ and bone formation around the coated implant than the uncoated implant.
With increasing usage of dental implants, the most prevailing concern among clinicians remains to be peri-implantitis. Peri-implantitis is observed despite the biocompatibility and osseointegration properties of titanium. Surface coatings with antimicrobial effectiveness can help in preventing the onset of peri-implantitis and bone loss, while increasing BIC.
牙科种植体在牙科中用于替代牙齿，恢复功能并提高患者的生活质量。骨整合对于牙科种植体的成功至关重要。种植体表面改性可以增强骨整合。由于其独特的物理化学性质，金纳米粒子已成为一种有前途的牙科种植体涂层材料。我们旨在回顾已发表的文献，评估金纳米粒子涂层对增加牙科种植体骨整合的影响。
数据库搜索共产生了 2011 年 1 月至 2021 年 12 月期间的 14 篇文章，其中 9 篇被排除在外，有 5 项研究符合纳入标准。所有研究都报告说，与未涂层对照相比，金纳米粒子涂层可提高骨整合的结果。
报道最多的骨整合结果是骨-种植体接触、去除扭矩（RTQ）和种植体周围骨形成的组织学分析。涂层种植体的平均 RTQ 值范围为 6.7 至 52.8 Ncm，而未涂层对照为 3.7 至 40.8 Ncm。组织学分析显示，涂层种植体周围的骨形成和密度大于未涂层种植体。金纳米粒子涂层似乎对骨整合有积极影响。纳入研究的结果表明，金纳米粒子涂层种植体比未涂层种植体促进更大的骨-种植体接触（BIC）、RTQ 和种植体周围的骨形成。
随着牙科种植体的使用越来越多，临床医生最关心的问题仍然是种植体周围炎。尽管钛具有生物相容性和骨整合特性，但仍观察到种植体周围炎和骨丢失。具有抗菌效果的表面涂层有助于预防种植体周围炎和骨丢失的发生，同时增加 BIC。
