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Drug development in the AI era: AlphaFold 3 is coming!

作者信息

Shi Yi

机构信息

CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing 100101, China.

Medical School, University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Innovation (Camb). 2024 Aug 14;5(5):100685. doi: 10.1016/j.xinn.2024.100685. eCollection 2024 Sep 9.

DOI:10.1016/j.xinn.2024.100685
PMID:39285906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11402749/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fac/11402749/c2f2c41faf90/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fac/11402749/c2f2c41faf90/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fac/11402749/c2f2c41faf90/gr1.jpg

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Nat Rev Microbiol. 2024 Aug;22(8):457. doi: 10.1038/s41579-024-01059-5.
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Accurate structure prediction of biomolecular interactions with AlphaFold 3.利用 AlphaFold 3 进行生物分子相互作用的精确结构预测。
Nature. 2024 Jun;630(8016):493-500. doi: 10.1038/s41586-024-07487-w. Epub 2024 May 8.
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Generalized biomolecular modeling and design with RoseTTAFold All-Atom.基于 RoseTTAFold All-Atom 的广义生物分子建模与设计。
猴痘病毒DNA复制保真度的结构基础。
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New Ground in Antifungal Discovery and Therapy for Invasive Fungal Infections: Innovations, Challenges, and Future Directions.侵袭性真菌感染的抗真菌发现与治疗新领域：创新、挑战与未来方向
J Fungi (Basel). 2024 Dec 15;10(12):871. doi: 10.3390/jof10120871.
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Cryo-EM structure of Nipah virus L-P polymerase complex.尼帕病毒L-P聚合酶复合物的冷冻电镜结构
Nat Commun. 2024 Dec 3;15(1):10524. doi: 10.1038/s41467-024-54994-5.
Science. 2024 Apr 19;384(6693):eadl2528. doi: 10.1126/science.adl2528.
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Artificial intelligence for science-bridging data to wisdom.用于科学的人工智能——将数据转化为智慧。
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