Sawraj Sushma, Kumar Dharmendra, Pravesh Ram, Shanker Chaudhary Vijay, Prasad Pandey Bramha, Sharma Sneha, Kumar Santosh
IEEE Trans Nanobioscience. 2025 Apr;24(2):157-164. doi: 10.1109/TNB.2024.3462748. Epub 2025 Mar 26.
The article provides a comprehensive overview of the current and future advances of Photonic crystal fiber (PCF) based biosensors, the research explores the impact of structural parameter variations on phase matching conditions, by investigating pitch, air hole diameter, and gold layer thickness. Currently, these surface plasmon resonance (SPR) biosensors demonstrate the ability to detect a range of biological substances such as glucose, pH, serum proteins, and similar chemicals. They have the capacity to directly identify bio-components in urine, blood, and saliva, as well as pathogens, bacteria, and contaminants in food, water, and air. The study investigates by presenting the fundamental principles of PCF biosensors, highlighting their comparative benefits over conventional biosensors. Recent studies utilizing PCF biosensors for various application are reviewed, the findings of the review suggest that the integration of SPR enhances the sensing capabilities of these biosensors, making them promising tools for diverse applications in the field of biosensing.
本文全面概述了基于光子晶体光纤（PCF）的生物传感器的当前及未来进展，该研究通过研究节距、气孔直径和金层厚度，探讨了结构参数变化对相位匹配条件的影响。目前，这些表面等离子体共振（SPR）生物传感器能够检测一系列生物物质，如葡萄糖、pH值、血清蛋白及类似化学物质。它们有能力直接识别尿液、血液和唾液中的生物成分，以及食品、水和空气中的病原体、细菌和污染物。该研究通过阐述光子晶体光纤生物传感器的基本原理进行调查，突出了它们相对于传统生物传感器的比较优势。综述了近期利用光子晶体光纤生物传感器进行各种应用的研究，综述结果表明，表面等离子体共振的整合增强了这些生物传感器的传感能力，使其成为生物传感领域各种应用的有前途的工具。
