Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Support Care Cancer. 2024 Sep 18;32(10):672. doi: 10.1007/s00520-024-08869-6.
The goal of this systematic review was to examine the effectiveness of e-health interventions for chemotherapy-induced nausea and vomiting (CINV).
A literature search was conducted across the databases of PubMed, Web of Science, Embase, CINAHL, and Cochrane Library from database establishment to 3 March 2024. We included randomized controlled trials in English where the intervention group was via e-health. Two reviewers independently carried out the screening, data extraction, and quality appraisal of the studies. Using Stata 17.0, meta-analyses were conducted to synthesize the effects of outcomes of interest.
A total of 6663 studies were retrieved, with only 8 RCTs meeting criteria, involving 620 patients. Meta-analysis revealed that e-health interventions significantly reduce CINV severity (MD = - 7.687; 95% CI - 11.903, - 3.326; p < 0.001). However, results regarding CINV incidence reduction and quality of life improvement are inconclusive due to variations in intervention content, modality, and frequency among studies.
e-health interventions may reduce the severity and incidence of CINV, while enhancing quality of life. However, the results should be interpreted cautiously. Higher quality studies are needed in the future to further validate the effectiveness of e-health interventions for CINV.
本系统评价的目的是评估电子健康干预措施在化疗引起的恶心和呕吐（CINV）中的有效性。
从数据库建立到 2024 年 3 月 3 日，我们在 PubMed、Web of Science、Embase、CINAHL 和 Cochrane Library 数据库中进行了文献检索。我们纳入了以英语发表的干预组采用电子健康的随机对照试验。两位评审员独立进行了研究的筛选、数据提取和质量评估。使用 Stata 17.0 进行荟萃分析，以综合感兴趣结局的效果。
共检索到 6663 项研究，仅有 8 项 RCT 符合标准，涉及 620 名患者。荟萃分析显示，电子健康干预措施可显著减轻 CINV 的严重程度（MD=-7.687；95%CI=-11.903，-3.326；p<0.001）。然而，由于研究中干预内容、方式和频率的差异，关于减少 CINV 发生率和提高生活质量的结果尚无定论。
电子健康干预措施可能减轻 CINV 的严重程度和发生率，同时提高生活质量。然而，结果应谨慎解释。未来需要更多高质量的研究来进一步验证电子健康干预措施在 CINV 中的有效性。
