Gött U, Friess D
Reg Anaesth. 1985 Jul;8(3):50-3.
After favourable experience with bupivacaine-CO2 for peridural anaesthesia we studied, whether carbonated Meaverine would have a shortened latency period also. In one hundred patients we found that the latency period of Meaverine-CO2 was shortened by about four minutes on average compared with mepivacaine hydrochloride. There were no significant differences in spread or in effect on circulation, heart rate or compatibility. Blood concentration estimations showed a rapid dose-related increase of the level within five to ten minutes.
在布比卡因 - 二氧化碳用于硬膜外麻醉取得良好经验后，我们研究了碳酸美维明是否也会有缩短的潜伏期。在100例患者中，我们发现与盐酸甲哌卡因相比，碳酸美维明的潜伏期平均缩短了约4分钟。在扩散、对循环、心率或相容性的影响方面没有显著差异。血药浓度测定显示，在5至10分钟内血药水平迅速呈剂量相关升高。
