[Peridural anesthesia with mepivacaine-CO2].

After favourable experience with bupivacaine-CO2 for peridural anaesthesia we studied, whether carbonated Meaverine would have a shortened latency period also. In one hundred patients we found that the latency period of Meaverine-CO2 was shortened by about four minutes on average compared with mepivacaine hydrochloride. There were no significant differences in spread or in effect on circulation, heart rate or compatibility. Blood concentration estimations showed a rapid dose-related increase of the level within five to ten minutes.