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用于眼电生理学研究的综合性图形视网膜电图数据集。

A comprehensive dataset of pattern electroretinograms for ocular electrophysiology research.

机构信息

Department of Statistics and Operations Research, University of Valladolid, Valladolid, 47011, Spain.

Institute of Applied Ophthalmobiology (IOBA), University of Valladolid, Valladolid, 47011, Spain.

出版信息

Sci Data. 2024 Sep 18;11(1):1013. doi: 10.1038/s41597-024-03857-1.

DOI:10.1038/s41597-024-03857-1
PMID:39294170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11410942/
Abstract

The Pattern Electroretinogram (PERG) is an essential tool in ophthalmic electrophysiology, providing an objective assessment of the central retinal function. It quantifies the activity of cells in the macula and the ganglion cells of the retina, assisting in the differentiation of macular and optic nerve conditions. In this study, we present the IOBA-PERG dataset, an extensive collection of 1354 transient PERG responses accessible on the PhysioNet repository. These recordings were conducted at the Institute of Applied Ophthalmobiology (IOBA) at University of Valladolid, over an extended period spanning nearly two decades, from 2003 to 2022. The dataset includes 336 records, ensuring at least one PERG signal per eye. The dataset thoughtfully includes demographic and clinical data, comprising information such as age, gender, visual acuity measurements, and expert diagnoses. This comprehensive dataset fills a gap in ocular electrophysiological repositories, enhancing ophthalmology research. Researchers can explore a broad range of eye-related conditions and diseases, leading to enhanced diagnostic accuracy, innovative treatment strategies, methodological advancements, and a deeper understanding of ocular electrophysiology.

摘要

图形视网膜电图(PERG)是眼科电生理学中的重要工具,为中央视网膜功能提供客观评估。它量化了黄斑和视网膜神经节细胞的活动,有助于区分黄斑和视神经病变。在这项研究中,我们展示了 IOBA-PERG 数据集,这是一个广泛的瞬态 PERG 反应数据集,可在 PhysioNet 存储库中获得。这些记录是在瓦拉多利德大学应用眼科生物学研究所(IOBA)进行的,跨越了近二十年的时间,从 2003 年到 2022 年。该数据集包括 336 个记录,确保每个眼睛至少有一个 PERG 信号。该数据集周到地包含了人口统计学和临床数据,包括年龄、性别、视力测量和专家诊断等信息。这个全面的数据集填补了眼电生理学存储库的空白,增强了眼科学研究。研究人员可以探索广泛的与眼睛相关的病症和疾病,从而提高诊断准确性、创新治疗策略、方法学进展,并深入了解眼电生理学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/f9ff33cfda24/41597_2024_3857_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/e781a989ca82/41597_2024_3857_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/ec5f81c93b2b/41597_2024_3857_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/aea8c74cc220/41597_2024_3857_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/318bb71169c3/41597_2024_3857_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/ae1e2e853c41/41597_2024_3857_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/f9ff33cfda24/41597_2024_3857_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/e781a989ca82/41597_2024_3857_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/ec5f81c93b2b/41597_2024_3857_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/aea8c74cc220/41597_2024_3857_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/318bb71169c3/41597_2024_3857_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/ae1e2e853c41/41597_2024_3857_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a75a/11410942/f9ff33cfda24/41597_2024_3857_Fig6_HTML.jpg

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本文引用的文献

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ISCEV standard for clinical pattern electroretinography (2024 update).国际临床电生理学会临床图形视网膜电图标准(2024 年更新)。
Doc Ophthalmol. 2024 Apr;148(2):75-85. doi: 10.1007/s10633-024-09970-1. Epub 2024 Mar 15.
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The electrophysiological assessment of visual function in Multiple Sclerosis.多发性硬化症视觉功能的电生理评估
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