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生活方式医学在常见激素紊乱中的作用:基于病例的讨论

Lifestyle Medicine's Role in Common Hormonal Disorders: A Case-Based Discussion.

作者信息

Gulati Mahima

机构信息

Endocrinology, Diabetes and Metabolism, Frank H. Netter School of Medicine, Quinnipiac University, North Haven, CT, USA (MG).

出版信息

Am J Lifestyle Med. 2024 Apr 3;18(5):638-647. doi: 10.1177/15598276241242012. eCollection 2024 Sep-Oct.

Abstract

Hormonal disorders like PCOS (Polycystic Ovary Syndrome), autoimmune thyroid disease (AITD) including Hashimoto's thyroiditis, male hypogonadism are commonly encountered in clinical practice in the US and worldwide, with rising frequency. These typically affect patients during young or middle age, compared with other common chronic illnesses like type 2 diabetes, hypertension, atherosclerotic cardiovascular disease, where onset may usually be in middle or older age. Multiple studies point to the role of disordered lifestyle health behaviors as contributory to these endocrinopathies, and conversely therapeutic lifestyle changes leading to improvement in signs, symptoms, biochemical markers, and sequelae of these conditions. This article presents 3 different real life case studies of the conditions enlisted above and documents the positive impact of lifestyle improvements on their disease condition. Therapeutic lifestyle behaviors are an extremely useful and important component of management of these familiar endocrinologic disorders, and clinicians need to routinely counsel their patients about healthy lifestyle interventions when treating these common syndromes.

摘要

像多囊卵巢综合征(PCOS)、自身免疫性甲状腺疾病(AITD),包括桥本甲状腺炎以及男性性腺功能减退等激素紊乱疾病,在美国及全球的临床实践中都很常见,且发病率呈上升趋势。与2型糖尿病、高血压、动脉粥样硬化性心血管疾病等其他常见慢性疾病通常在中年或老年发病不同,这些激素紊乱疾病通常影响年轻或中年患者。多项研究指出,不良的生活方式健康行为会导致这些内分泌疾病,相反,治疗性的生活方式改变会改善这些疾病的体征、症状、生化指标及后遗症。本文介绍了上述三种疾病的三个不同的真实病例研究,并记录了生活方式改善对其病情的积极影响。治疗性的生活方式行为是这些常见内分泌疾病管理中极其有用且重要的组成部分,临床医生在治疗这些常见综合征时需要定期向患者提供关于健康生活方式干预的建议。

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