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生活方式医学在常见激素紊乱中的作用:基于病例的讨论

Lifestyle Medicine's Role in Common Hormonal Disorders: A Case-Based Discussion.

作者信息

Gulati Mahima

机构信息

Endocrinology, Diabetes and Metabolism, Frank H. Netter School of Medicine, Quinnipiac University, North Haven, CT, USA (MG).

出版信息

Am J Lifestyle Med. 2024 Apr 3;18(5):638-647. doi: 10.1177/15598276241242012. eCollection 2024 Sep-Oct.

DOI:10.1177/15598276241242012
PMID:39309326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11412375/
Abstract

Hormonal disorders like PCOS (Polycystic Ovary Syndrome), autoimmune thyroid disease (AITD) including Hashimoto's thyroiditis, male hypogonadism are commonly encountered in clinical practice in the US and worldwide, with rising frequency. These typically affect patients during young or middle age, compared with other common chronic illnesses like type 2 diabetes, hypertension, atherosclerotic cardiovascular disease, where onset may usually be in middle or older age. Multiple studies point to the role of disordered lifestyle health behaviors as contributory to these endocrinopathies, and conversely therapeutic lifestyle changes leading to improvement in signs, symptoms, biochemical markers, and sequelae of these conditions. This article presents 3 different real life case studies of the conditions enlisted above and documents the positive impact of lifestyle improvements on their disease condition. Therapeutic lifestyle behaviors are an extremely useful and important component of management of these familiar endocrinologic disorders, and clinicians need to routinely counsel their patients about healthy lifestyle interventions when treating these common syndromes.

摘要

像多囊卵巢综合征(PCOS)、自身免疫性甲状腺疾病(AITD),包括桥本甲状腺炎以及男性性腺功能减退等激素紊乱疾病,在美国及全球的临床实践中都很常见,且发病率呈上升趋势。与2型糖尿病、高血压、动脉粥样硬化性心血管疾病等其他常见慢性疾病通常在中年或老年发病不同,这些激素紊乱疾病通常影响年轻或中年患者。多项研究指出,不良的生活方式健康行为会导致这些内分泌疾病,相反,治疗性的生活方式改变会改善这些疾病的体征、症状、生化指标及后遗症。本文介绍了上述三种疾病的三个不同的真实病例研究,并记录了生活方式改善对其病情的积极影响。治疗性的生活方式行为是这些常见内分泌疾病管理中极其有用且重要的组成部分,临床医生在治疗这些常见综合征时需要定期向患者提供关于健康生活方式干预的建议。

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本文引用的文献

1
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome.2023 年多囊卵巢综合征评估和管理国际循证指南推荐。
J Clin Endocrinol Metab. 2023 Sep 18;108(10):2447-2469. doi: 10.1210/clinem/dgad463.
2
Effect of gluten-free diet on autoimmune thyroiditis progression in patients with no symptoms or histology of celiac disease: a meta-analysis.无乳糜泻症状或组织学证据的患者中,无麸质饮食对自身免疫性甲状腺炎进展的影响:一项荟萃分析。
Front Endocrinol (Lausanne). 2023 Jul 24;14:1200372. doi: 10.3389/fendo.2023.1200372. eCollection 2023.
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Thyroid, Diet, and Alternative Approaches.甲状腺、饮食与替代方法。
J Clin Endocrinol Metab. 2022 Nov 23;107(11):2973-2981. doi: 10.1210/clinem/dgac473.
4
Daily physical activity is negatively associated with thyroid hormone levels, inflammation, and immune system markers among men and women in the NHANES dataset.在 NHANES 数据集中,男性和女性的日常体力活动与甲状腺激素水平、炎症和免疫系统标志物呈负相关。
PLoS One. 2022 Jul 6;17(7):e0270221. doi: 10.1371/journal.pone.0270221. eCollection 2022.
5
Prevalence and associated risk factors for mental health problems among patients with polycystic ovary syndrome in Bangladesh: A nationwide cross-Sectional study.孟加拉国多囊卵巢综合征患者心理健康问题的流行状况及相关危险因素:一项全国性横断面研究。
PLoS One. 2022 Jun 22;17(6):e0270102. doi: 10.1371/journal.pone.0270102. eCollection 2022.
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Ethnic diversity and burden of polycystic ovary syndrome among US adolescent females.美国青春期女性的种族多样性和多囊卵巢综合征负担。
J Pediatr Endocrinol Metab. 2022 May 23;35(6):821-825. doi: 10.1515/jpem-2022-0160. Print 2022 Jun 27.
7
Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment.桥本甲状腺炎:病因、诊断和治疗的循证指南。
Pol Arch Intern Med. 2022 Mar 30;132(3). doi: 10.20452/pamw.16222. Epub 2022 Mar 3.
8
Hormones can influence drug addiction-A narrative review.激素可影响药物成瘾——一篇叙述性综述。
Biomedicine (Taipei). 2021 Jun 1;11(2):5-10. doi: 10.37796/2211-8039.1120. eCollection 2021.
9
Relationship Between Loneliness and Hypothyroidism.孤独与甲状腺功能减退症之间的关系。
Cureus. 2021 Nov 28;13(11):e19955. doi: 10.7759/cureus.19955. eCollection 2021 Nov.
10
Thyroid Dysfunction and Sleep Disorders.甲状腺功能紊乱与睡眠障碍。
Front Endocrinol (Lausanne). 2021 Aug 24;12:725829. doi: 10.3389/fendo.2021.725829. eCollection 2021.