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美国麻疹疫苗接种对健康的影响。

Health impact of measles vaccination in the United States.

作者信息

Bloch A B, Orenstein W A, Stetler H C, Wassilak S G, Amler R W, Bart K J, Kirby C D, Hinman A R

出版信息

Pediatrics. 1985 Oct;76(4):524-32.

PMID:3931045
Abstract

As a result of intensive efforts to vaccinate children, measles and its attendant complications of encephalitis and death have declined more than 99% from the prevaccine era. Similarly, subacute sclerosing panencephalitis has declined markedly. Measles vaccine has been demonstrated to be extremely safe, as well as extremely effective. The health and resource benefits due to vaccination against measles during the first 20 years of vaccine licensure have been enormous. In this period it is estimated that vaccination against measles has prevented 52 million cases, 5,200 deaths, and 17,400 cases of mental retardation, achieving a net savings of $5.1 billion. These substantial health and resource benefits of measles vaccination will continue to accrue in the future.

摘要

由于大力开展儿童疫苗接种工作,麻疹及其相关的脑炎并发症和死亡病例比疫苗接种前时代减少了99%以上。同样,亚急性硬化性全脑炎也显著减少。麻疹疫苗已被证明极其安全且极其有效。在疫苗获得许可的头20年里,接种麻疹疫苗带来的健康和资源效益是巨大的。据估计,在此期间,麻疹疫苗接种预防了5200万例病例、5200例死亡和17400例智力迟钝病例,实现了51亿美元的净节约。麻疹疫苗接种带来的这些巨大健康和资源效益在未来将继续显现。

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1
Health impact of measles vaccination in the United States.美国麻疹疫苗接种对健康的影响。
Pediatrics. 1985 Oct;76(4):524-32.
2
Epidemiologic studies of measles, measles vaccine, and subacute sclerosing panencephalitis.麻疹、麻疹疫苗与亚急性硬化性全脑炎的流行病学研究
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Subacute sclerosing panencephalitis: more cases of this fatal disease are prevented by measles immunization than was previously recognized.亚急性硬化性全脑炎:通过麻疹免疫预防的这种致命疾病病例比之前认为的更多。
J Infect Dis. 2005 Nov 15;192(10):1686-93. doi: 10.1086/497169. Epub 2005 Oct 12.
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Measles and mumps immunization: benefit versus risk factors.麻疹和腮腺炎免疫接种:益处与风险因素
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[Reasons for vaccinating against measles].[接种麻疹疫苗的原因]
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Measles and subacute sclerosing panencephalitis. An argument for intensified vaccination in Australia.麻疹与亚急性硬化性全脑炎。关于澳大利亚强化疫苗接种的争论。
Med J Aust. 1984 Sep 15;141(6):325-7.
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Measles, measles vaccination, and risk of subacute sclerosing panencephalitis (SSPE).麻疹、麻疹疫苗接种与亚急性硬化性全脑炎(SSPE)风险
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Review of the effect of measles vaccination on the epidemiology of SSPE.麻疹疫苗接种对亚急性硬化性全脑炎流行病学影响的综述。
Int J Epidemiol. 2007 Dec;36(6):1334-48. doi: 10.1093/ije/dym207. Epub 2007 Nov 23.
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Subacute sclerosing panencephalitis mortality, United States, 1979-2016: Vaccine-induced declines in SSPE deaths.亚急性硬化性全脑炎死亡率,美国,1979-2016 年:疫苗接种导致 SSPE 死亡人数下降。
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Measles--United States, 2005.麻疹——美国,2005年
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