Bloch A B, Orenstein W A, Stetler H C, Wassilak S G, Amler R W, Bart K J, Kirby C D, Hinman A R
Pediatrics. 1985 Oct;76(4):524-32.
As a result of intensive efforts to vaccinate children, measles and its attendant complications of encephalitis and death have declined more than 99% from the prevaccine era. Similarly, subacute sclerosing panencephalitis has declined markedly. Measles vaccine has been demonstrated to be extremely safe, as well as extremely effective. The health and resource benefits due to vaccination against measles during the first 20 years of vaccine licensure have been enormous. In this period it is estimated that vaccination against measles has prevented 52 million cases, 5,200 deaths, and 17,400 cases of mental retardation, achieving a net savings of $5.1 billion. These substantial health and resource benefits of measles vaccination will continue to accrue in the future.
由于大力开展儿童疫苗接种工作,麻疹及其相关的脑炎并发症和死亡病例比疫苗接种前时代减少了99%以上。同样,亚急性硬化性全脑炎也显著减少。麻疹疫苗已被证明极其安全且极其有效。在疫苗获得许可的头20年里,接种麻疹疫苗带来的健康和资源效益是巨大的。据估计,在此期间,麻疹疫苗接种预防了5200万例病例、5200例死亡和17400例智力迟钝病例,实现了51亿美元的净节约。麻疹疫苗接种带来的这些巨大健康和资源效益在未来将继续显现。