East Carolina University School of Dental Medicine, Greenville, North Carolina, USA.
Monogr Oral Sci. 2024;32:140-146. doi: 10.1159/000538875. Epub 2024 Jul 1.
Much effort has been spent in the identification of an environmental factor that explains the occurrence of molar incisor hypomineralisation (MIH). The best explanation, however, is accepting that MIH has a complex or multifactorial mode of inheritance. This chapter provides an analysis of how multifactorial inheritance operates in determining MIH, an explanation that accommodates the variation seen in the phenotype and the frequency of the problem around the world.
人们花费了大量精力来确定一个环境因素，以解释磨牙和切牙釉质发育不全（MIH）的发生。然而，最好的解释是接受 MIH 具有复杂的或多因素遗传模式。本章分析了多因素遗传如何在决定 MIH 中起作用，这种解释考虑到了表型的变异性和世界各地该问题的发生频率。
