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酵母中交配型基因座对STA1基因表达的调控。

Control of STA1 gene expression by the mating-type locus in yeasts.

作者信息

Yamashita I, Takano Y, Fukui S

出版信息

J Bacteriol. 1985 Nov;164(2):769-73. doi: 10.1128/jb.164.2.769-773.1985.

DOI:10.1128/jb.164.2.769-773.1985
PMID:3932329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC214318/
Abstract

Extracellular production of glucoamylase from the yeast Saccharomyces diastaticus carrying an STA1 gene (a structural gene for the enzyme) is repressed by the mating-type constitution a/alpha. We obtained mutants that were relieved from the mating-type control of the STA1 gene expression. Tetrad analysis showed that the mutation was closely linked to MATa. The mutation was complemented by a MATa2 gene; hence, it was designated mata2. Northern blot analysis revealed that the MATa2-mediated repression occurs at the posttranscriptional level.

摘要

携带STA1基因（该酶的结构基因）的糖化酵母胞外产生的葡糖淀粉酶受交配型组成a/α的抑制。我们获得了从STA1基因表达的交配型控制中解脱出来的突变体。四分体分析表明该突变与MATa紧密连锁。该突变由MATa2基因互补；因此，它被命名为mata2。Northern印迹分析显示MATa2介导的抑制发生在转录后水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/e8bc908988e2/jbacter00216-0287-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/f3fbd4759b42/jbacter00216-0286-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/336875f14b77/jbacter00216-0287-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/e8bc908988e2/jbacter00216-0287-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/f3fbd4759b42/jbacter00216-0286-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/336875f14b77/jbacter00216-0287-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/214318/e8bc908988e2/jbacter00216-0287-b.jpg

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Control of STA1 gene expression by the mating-type locus in yeasts.酵母中交配型基因座对STA1基因表达的调控。
J Bacteriol. 1985 Nov;164(2):769-73. doi: 10.1128/jb.164.2.769-773.1985.
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引用本文的文献

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FLO11, a yeast gene related to the STA genes, encodes a novel cell surface flocculin.FLO11是一个与STA基因相关的酵母基因，编码一种新型细胞表面絮凝蛋白。
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本文引用的文献

1
The sequence of the DNAs coding for the mating-type loci of Saccharomyces cerevisiae.酿酒酵母交配型基因座的编码DNA序列。
Cell. 1981 Nov;27(1 Pt 2):15-23. doi: 10.1016/0092-8674(81)90356-1.
2
Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.酵母交配型相互转换的调控：交配型基因座对HO基因表达的反馈控制
Proc Natl Acad Sci U S A. 1983 May;80(10):3035-9. doi: 10.1073/pnas.80.10.3035.
3
In vivo ligation of linear DNA molecules to circular forms in the yeast Saccharomyces cerevisiae.
酿酒酵母中DNA修复的α/α控制：遗传和生理方面
Genetics. 1993 Mar;133(3):489-98. doi: 10.1093/genetics/133.3.489.
4
Properties and engineering of a mutant STA promoter of Saccharomyces diastaticus.糖化酵母突变STA启动子的特性与工程研究
Appl Biochem Biotechnol. 1994 Feb;44(2):187-204. doi: 10.1007/BF02921654.
5
Cloning of a new allelic variant of a Saccharomyces diastaticus glucoamylase gene and its introduction into industrial yeasts.糖化酵母葡糖淀粉酶基因新等位变体的克隆及其导入工业酵母
Appl Biochem Biotechnol. 1994 Feb;44(2):161-85. doi: 10.1007/BF02921653.
6
Gene fusion is a possible mechanism underlying the evolution of STA1.基因融合是STA1进化背后的一种可能机制。
J Bacteriol. 1987 May;169(5):2142-9. doi: 10.1128/jb.169.5.2142-2149.1987.
7
Transcriptional control of glucoamylase synthesis in vegetatively growing and sporulating Saccharomyces species.营养生长和产孢酵母物种中葡糖淀粉酶合成的转录调控
Mol Cell Biol. 1986 Sep;6(9):3034-41. doi: 10.1128/mcb.6.9.3034-3041.1986.
8
Expression of a Bacillus alpha-amylase gene in yeast.芽孢杆菌α-淀粉酶基因在酵母中的表达。
Curr Genet. 1988 Jul;14(1):1-8. doi: 10.1007/BF00405846.
9
Regulation of STA1 gene expression by MAT during the life cycle of Saccharomyces cerevisiae.酿酒酵母生命周期中MAT对STA1基因表达的调控。
Mol Cell Biol. 1989 Sep;9(9):3992-8. doi: 10.1128/mcb.9.9.3992-3998.1989.
10
Differential regulation of STA genes of Saccharomyces cerevisiae.酿酒酵母STA基因的差异调控
Mol Gen Genet. 1990 Jun;222(1):87-96. doi: 10.1007/BF00283028.
在酿酒酵母中，将线性DNA分子在体内连接成环状形式。
J Bacteriol. 1983 Aug;155(2):747-54. doi: 10.1128/jb.155.2.747-754.1983.
4
Movement of yeast transposable elements by gene conversion.酵母转座元件通过基因转换进行的移动。
Proc Natl Acad Sci U S A. 1982 Sep;79(18):5621-5. doi: 10.1073/pnas.79.18.5621.
5
In vitro mutation analysis of the mating-type locus in yeast.酵母交配型基因座的体外突变分析
Cell. 1981 Nov;27(1 Pt 2):25-35. doi: 10.1016/0092-8674(81)90357-3.
6
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Cell. 1981 Feb;23(2):605-14. doi: 10.1016/0092-8674(81)90156-2.
7
A position effect in the control of transcription at yeast mating type loci.酵母交配型基因座转录调控中的位置效应。
Nature. 1981 Jan 22;289(5795):244-50. doi: 10.1038/289244a0.
8
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Nature. 1981 Jan 22;289(5795):239-44. doi: 10.1038/289239a0.
9
Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genes.交配信号控制着因一个可转座重复元件插入到多种酵母基因附近而产生的突变的表达。
Cell. 1980 Nov;22(2 Pt 2):427-36. doi: 10.1016/0092-8674(80)90353-0.
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Proc Natl Acad Sci U S A. 1983 May;80(9):2432-6. doi: 10.1073/pnas.80.9.2432.