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用于神经肌肉检查自动评分的人工智能远程医疗

AI-Powered Telemedicine for Automatic Scoring of Neuromuscular Examinations.

作者信息

Lesport Quentin, Palmie Davis, Öztosun Gülşen, Kaminski Henry J, Garbey Marc

机构信息

Care Constitution Corp., Newark, DE 19702, USA.

Laboratoire des Sciences de l'Ingénieur pour l'Environnement (LaSIE) UMR-CNRS 7356, University of La Rochelle, 17000 La Rochelle, France.

出版信息

Bioengineering (Basel). 2024 Sep 20;11(9):942. doi: 10.3390/bioengineering11090942.

DOI:10.3390/bioengineering11090942
PMID:39329684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11429301/
Abstract

Telemedicine is now being used more frequently to evaluate patients with myasthenia gravis (MG). Assessing this condition involves clinical outcome measures, such as the standardized MG-ADL scale or the more complex MG-CE score obtained during clinical exams. However, human subjectivity limits the reliability of these examinations. We propose a set of AI-powered digital tools to improve scoring efficiency and quality using computer vision, deep learning, and natural language processing. This paper focuses on automating a standard telemedicine video by segmenting it into clips corresponding to the MG-CE assessment. This AI-powered solution offers a quantitative assessment of neurological deficits, improving upon subjective evaluations prone to examiner variability. It has the potential to enhance efficiency, patient participation in MG clinical trials, and broader applicability to various neurological diseases.

摘要

远程医疗目前正更频繁地用于评估重症肌无力(MG)患者。评估这种疾病涉及临床结局指标,如标准化的MG-ADL量表或临床检查期间获得的更复杂的MG-CE评分。然而,人为主观性限制了这些检查的可靠性。我们提出了一套由人工智能驱动的数字工具,利用计算机视觉、深度学习和自然语言处理来提高评分效率和质量。本文重点通过将标准远程医疗视频分割成与MG-CE评估相对应的片段来实现其自动化。这种由人工智能驱动的解决方案提供了对神经功能缺损的定量评估,改进了容易因检查者差异而产生的主观评估。它有可能提高效率、增加患者对MG临床试验的参与度,并更广泛地应用于各种神经系统疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/647ca61003ca/bioengineering-11-00942-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/42cafc113987/bioengineering-11-00942-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/23567208c3e6/bioengineering-11-00942-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/be45c31c9b63/bioengineering-11-00942-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/824dcc6c25a8/bioengineering-11-00942-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/3b3f2b72951a/bioengineering-11-00942-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/5089c8023c5f/bioengineering-11-00942-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/647ca61003ca/bioengineering-11-00942-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/42cafc113987/bioengineering-11-00942-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/23567208c3e6/bioengineering-11-00942-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/be45c31c9b63/bioengineering-11-00942-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/824dcc6c25a8/bioengineering-11-00942-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/3b3f2b72951a/bioengineering-11-00942-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/5089c8023c5f/bioengineering-11-00942-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/11429301/647ca61003ca/bioengineering-11-00942-g007.jpg

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J Clin Transl Sci. 2023 Nov 30;7(1):e268. doi: 10.1017/cts.2023.660. eCollection 2023.
2
Eye Segmentation Method for Telehealth: Application to the Myasthenia Gravis Physical Examination.远程医疗中的眼部分割方法:在重症肌无力体格检查中的应用。
Sensors (Basel). 2023 Sep 7;23(18):7744. doi: 10.3390/s23187744.
3
A Digital Telehealth System to Compute the Myasthenia Gravis Core Examination Metrics.
一种用于计算重症肌无力核心检查指标的数字远程医疗系统。
JMIR Neurotechnol. 2023;2. doi: 10.2196/43387. Epub 2023 Apr 19.
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Addressing Outcome Measure Variability in Myasthenia Gravis Clinical Trials.解决重症肌无力临床试验中的结局测量变异性问题。
Neurology. 2023 Sep 5;101(10):442-451. doi: 10.1212/WNL.0000000000207278. Epub 2023 Apr 19.
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Graphical user interface design to improve understanding of the patient-reported outcome symptom response.图形用户界面设计以提高对患者报告的结局症状反应的理解。
PLoS One. 2023 Jan 24;18(1):e0278465. doi: 10.1371/journal.pone.0278465. eCollection 2023.
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The best and worst of times in therapy development for myasthenia gravis.重症肌无力治疗研究的最好和最坏时期。
Muscle Nerve. 2023 Jan;67(1):12-16. doi: 10.1002/mus.27742. Epub 2022 Nov 12.
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