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盐胁迫下（螺旋藻）混养：对生物量组成、脂肪酸甲酯谱和藻蓝蛋白含量的影响。

Mixotrophic Cultivation of (Spirulina) under Salt Stress: Effect on Biomass Composition, FAME Profile and Phycocyanin Content.

机构信息

Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 287, 41123 Modena, MO, Italy.

Teregroup Srl, Via David Livingstone 37, 41123 Modena, MO, Italy.

出版信息

Mar Drugs. 2024 Aug 24;22(9):381. doi: 10.3390/md22090381.

DOI:10.3390/md22090381
PMID:39330262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11433411/
Abstract

holds promise for biotechnological applications due to its rapid growth and ability to produce valuable bioactive compounds like phycocyanin (PC). This study explores the impact of salinity and brewery wastewater (BWW) on the mixotrophic cultivation of . Utilizing BWW as an organic carbon source and seawater (SW) for salt stress, we aim to optimize PC production and biomass composition. Under mixotrophic conditions with 2% BWW and SW, showed enhanced biomass productivity, reaching a maximum of 3.70 g L and significant increases in PC concentration. This study also observed changes in biochemical composition, with elevated protein and carbohydrate levels under salt stress that mimics the use of seawater. Mixotrophic cultivation with BWW and SW also influenced the FAME profile, enhancing the content of C16:0 and C18:1 FAMES. The purity (EP of 1.15) and yield (100 mg g) of PC were notably higher in mixotrophic cultures, indicating the potential for commercial applications in food, cosmetics, and pharmaceuticals. This research underscores the benefits of integrating the use of saline water with waste valorization in microalgae cultivation, promoting sustainability and economic efficiency in biotechnological processes.

摘要

由于其快速生长和生产有价值的生物活性化合物（如藻蓝蛋白）的能力，在生物技术应用方面具有广阔的前景。本研究探讨了盐度和啤酒废水（BWW）对混合营养培养的影响。利用 BWW 作为有机碳源和海水（SW）来模拟盐胁迫，我们旨在优化 PC 的生产和生物质组成。在 2% BWW 和 SW 的混合营养条件下，表现出更高的生物量生产力，最大达到 3.70 g/L，并且 PC 浓度显著增加。本研究还观察到了生物化学组成的变化，在模拟海水使用的盐胁迫下，蛋白质和碳水化合物水平升高。BWW 和 SW 的混合营养培养也影响了 FAME 谱，增加了 C16:0 和 C18:1 FAMES 的含量。混合营养培养中藻蓝蛋白的纯度（EP 为 1.15）和产量（100 mg/g）显著提高，表明在食品、化妆品和制药领域具有商业应用的潜力。这项研究强调了将盐水利用与微藻培养中的废物增值相结合的好处，促进了生物技术过程的可持续性和经济效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/2836abea73f1/marinedrugs-22-00381-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/9e2a01ec3dac/marinedrugs-22-00381-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/7de6570f1806/marinedrugs-22-00381-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/c4f2f9e1d9bd/marinedrugs-22-00381-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/10abea3e8518/marinedrugs-22-00381-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/2836abea73f1/marinedrugs-22-00381-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/9e2a01ec3dac/marinedrugs-22-00381-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/7de6570f1806/marinedrugs-22-00381-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/c4f2f9e1d9bd/marinedrugs-22-00381-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/10abea3e8518/marinedrugs-22-00381-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc4/11433411/2836abea73f1/marinedrugs-22-00381-g005.jpg

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Chemosphere. 2024 Apr;353:141387. doi: 10.1016/j.chemosphere.2024.141387. Epub 2024 Feb 6.
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Harnessing the potential: advances in cyanobacterial natural product research and biotechnology.
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