Tikhonova O V, Lur'e L M, Bartoshevich Iu E
Antibiot Med Biotekhnol. 1985 Jun;30(6):423-8.
Addition of liquid vegetable oils to nutrient media decreased the intensity of penicillin biosynthesis. The unfavourable effect of the oils was more pronounced at the beginning of the process while they were not completely utilized. Sunflower oil is a readily assimilated source of carbon. The rate of its consumption is higher than that of whale oil or lactose. Like the majority of readily oxidized sources of carbon, sunflower oil must be a repressor of beta-galactosidase and the enzymes of penicillin biosynthesis.
向营养培养基中添加液态植物油会降低青霉素生物合成的强度。在该过程开始时，当植物油尚未被完全利用时，其不利影响更为明显。向日葵油是一种易于被同化的碳源。其消耗速率高于鲸油或乳糖。与大多数易于氧化的碳源一样，向日葵油必定是β-半乳糖苷酶和青霉素生物合成酶的阻遏物。
