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用于组织工程、控释和土壤修复的可生物降解天然水凝胶

Biodegradable Natural Hydrogels for Tissue Engineering, Controlled Release, and Soil Remediation.

作者信息

Garcia-Garcia Ane, Muñana-González Sara, Lanceros-Mendez Senentxu, Ruiz-Rubio Leire, Alvarez Leyre Perez, Vilas-Vilela José Luis

机构信息

Macromolecular Chemistry Group (LABQUIMAC), Physical Chemistry Department, Faculty of Science and Technology, University of the Basque Country UPV/EHU, 48940 Leioa, Spain.

BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain.

出版信息

Polymers (Basel). 2024 Sep 14;16(18):2599. doi: 10.3390/polym16182599.

DOI:10.3390/polym16182599
PMID:39339063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11435712/
Abstract

This article provides insights into hydrogels of the most promising biodegradable natural polymers and their mechanisms of degradation, highlighting the different possibilities of controlling hydrogel degradation rates. Since biodegradable hydrogels can be designed as scaffolding materials to mimic the physical and biochemical properties of natural tissues, these hydrogels have found widespread application in the field of tissue engineering and controlled release. In the same manner, their potential as water reservoirs, macro- and microelement carriers, or matrixes for the selective adsorption of pollutants make them excellent candidates for sustainable soil amendment solutions. Accordingly, this article summarizes the recent advances in natural biodegradable hydrogels in the fields of tissue engineering, controlled release, and soil remediation, emphasizing the new opportunities that degradability and its tunability offer for the design and applicability of hydrogels.

摘要

本文深入探讨了最具前景的可生物降解天然聚合物水凝胶及其降解机制，突出了控制水凝胶降解速率的不同可能性。由于可生物降解水凝胶可设计为支架材料以模拟天然组织的物理和生化特性，这些水凝胶已在组织工程和控释领域得到广泛应用。同样，它们作为水库、宏观和微量元素载体或污染物选择性吸附基质的潜力，使其成为可持续土壤改良解决方案的理想候选者。因此，本文总结了天然可生物降解水凝胶在组织工程、控释和土壤修复领域的最新进展，强调了降解性及其可调性为水凝胶的设计和适用性带来的新机遇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/b8cbdbd6d19c/polymers-16-02599-g015.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/b05b9c5462c4/polymers-16-02599-g011.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/1b8f2dca1338/polymers-16-02599-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/dc8622c65da1/polymers-16-02599-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/dd7b2966265d/polymers-16-02599-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/2b6f51ff1df6/polymers-16-02599-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/4ad5bb99a142/polymers-16-02599-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/2a5dcda3158c/polymers-16-02599-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/9a8eecfa9f24/polymers-16-02599-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/e08b25d53324/polymers-16-02599-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/fe97a22a94fd/polymers-16-02599-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/cd38eb4094e8/polymers-16-02599-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/1fde7ce04aa8/polymers-16-02599-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/b05b9c5462c4/polymers-16-02599-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/e4fb5d3e7970/polymers-16-02599-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/1b8f2dca1338/polymers-16-02599-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/bbb8afcb63c6/polymers-16-02599-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc01/11435712/b8cbdbd6d19c/polymers-16-02599-g015.jpg

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