Center for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans' Hospital, Madison, WI, USA.
Center for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans' Hospital, Madison, WI, USA.
Drug Alcohol Depend. 2024 Nov 1;264:112436. doi: 10.1016/j.drugalcdep.2024.112436. Epub 2024 Sep 19.
Understanding the motivational processes that influence e-cigarette use in a laboratory setting may help elucidate mechanisms that support long-term ecigarette use, which could have significant clinical and public health consequences.
Secondary analyses were conducted on data from exclusive smokers (N=47) and dual users (N=88) who underwent a laboratory ad lib use session. Participants were given 10minutes to smoke (exclusive smokers) or vape (dual users) as much as they wanted. Withdrawal was assessed pre- and post-use. Smoking and vaping behavior was coded from session videos. Person-level predictors included cigarette/ecigarette craving-relief expectancies, demographics, and cigarette/e-cigarette use and dependence. Smoking and vaping status was assessed at Year 1 using self-reported 30-day point prevalence. Data were analyzed using general linear models and logistic regressions.
Both groups reported reductions in withdrawal after product use, including cigarette craving. Baseline e-cigarette craving-relief expectancies, pre-session ecigarette craving, heaviness of e-cigarette use, and relative e-cigarette dependence were significant univariate predictors of continued vaping in dual users at Year 1 (ORs>1.04, ps<.05). Dual users and exclusive smokers did not differ on use behavior (i.e., average number of puffs, ps>.16).
E-cigarette use alleviated withdrawal, including cigarette and e-cigarette craving, in dual users. Laboratory use behavior did not differ between dual users using e-cigarettes and exclusive smokers using cigarettes. Greater e-cigarette craving-relief expectancies, e-cigarette craving, heaviness of e-cigarette use, and morning product use pattern ('relative dependence') may reflect mechanisms that sustain e-cigarette use.
在实验室环境中理解影响电子烟使用的动机过程,可能有助于阐明支持长期电子烟使用的机制,这可能会产生重大的临床和公共卫生后果。
对仅吸烟人群(N=47)和双重使用者(N=88)进行了实验室自由使用阶段数据的二次分析。参与者有 10 分钟的时间随意吸烟(仅吸烟人群)或吸电子烟(双重使用者)。在使用前后评估戒断情况。从会议视频中对吸烟和吸电子烟行为进行编码。个体水平的预测因素包括香烟/电子烟渴求缓解预期、人口统计学特征以及香烟/电子烟使用和依赖情况。使用自我报告的 30 天点患病率在第 1 年评估吸烟和吸电子烟状态。使用一般线性模型和逻辑回归进行数据分析。
两组人群在使用产品后都报告了戒断症状减轻,包括对香烟的渴求感减轻。电子烟渴求缓解预期、使用前电子烟渴求感、电子烟使用量和电子烟相对依赖程度等基线水平的电子烟渴求缓解预期,是双重使用者在第 1 年继续吸电子烟的显著单因素预测指标(ORs>1.04,p<.05)。双重使用者和仅吸烟者在使用行为上没有差异(即,平均吸烟量,p>.16)。
电子烟使用减轻了双重使用者的戒断症状,包括香烟和电子烟的渴求感。双重使用者使用电子烟和仅吸烟者使用香烟的实验室使用行为没有差异。更大的电子烟渴求缓解预期、电子烟渴求感、电子烟使用量和早上使用产品的模式(“相对依赖”)可能反映了维持电子烟使用的机制。