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吸烟和尼古丁依赖在开始使用电子烟后如何变化?双重使用者的回顾性分析。

How Does Smoking and Nicotine Dependence Change After Onset of Vaping? A Retrospective Analysis of Dual Users.

机构信息

Department of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.

Clinical Unit of Addictive Behaviors, Department of Psychology, University of Oviedo, Spain.

出版信息

Nicotine Tob Res. 2020 Apr 21;22(5):764-770. doi: 10.1093/ntr/ntz043.

Abstract

INTRODUCTION

Although some smokers switch to exclusive use of electronic cigarettes (e-cigarettes), others become dual users of combustible cigarettes and e-cigarettes. Little is known about how the onset of vaping affects the use of and dependence on combustible cigarettes or total nicotine use and dependence, which may influence health-related and cessation outcomes. Using self-report data of current combustible and e-cigarette use and retrospective recall of pre-vaping smoking in a sample of dual users, the aims of this study were (1) to compare pre- and post-vaping number of cigarettes per day and combustible cigarette dependence; (2) to compare pre- and post-vaping total nicotine use frequency (number of vaping sessions and cigarettes smoked per day), and total nicotine dependence; and (3) to examine predictors of nicotine dependence.

METHODS

We used baseline data from a smoking cessation trial with 2896 dual users. Nicotine use frequency and the Heaviness of Smoking Index were used as measures of nicotine use and dependence, respectively.

RESULTS

Participants decreased cigarettes/day from pre- (M = 19.24, SD = 9.01) to post-vaping (M = 11.15, SD = 8.02, p < .0001) and combustible cigarette dependence declined from pre- (M = 3.55, SD = 1.51) to post-vaping (M = 2.11, SD = 1.60, p < .0001). Total daily nicotine use frequency increased after initiating vaping (M = 19.25, SD = 9.01 vs. M = 29.46, SD = 8.61; p < .0001), as did total nicotine dependence (M = 3.55, SD = 1.51 vs. M = 4.68, SD = 1.38; p < .0001). Hierarchical regression analyses indicated that variables associated with greater overall nicotine dependence included: younger age, lower education, more years smoking, higher pre-vaping nicotine dependence, using e-cigarettes more days per month, more puffs per vaping session, higher e-liquid nicotine concentration, and longer vaping history.

CONCLUSIONS

Dual use leads to a reduction in the number of combustible cigarettes, but total nicotine use and dependence increases.

IMPLICATIONS

In dual users, a reduction in smoking following onset of vaping may offer some harm reduction via reduction in cigarette intake. However, the increase in total nicotine use and dependence could affect the ability to quit either or both products.

摘要

简介

尽管有些吸烟者转而只使用电子烟(电子烟),但其他人则成为可燃香烟和电子烟的双重使用者。关于电子烟的使用如何影响可燃香烟的使用和依赖,或者总尼古丁的使用和依赖,这可能会影响与健康相关的结果和戒烟结果,人们知之甚少。本研究使用了一项在双用户样本中进行的关于当前可燃和电子烟使用的自我报告数据以及对吸烟前电子烟使用的回顾性回忆,其目的是:(1)比较电子烟使用前后的每日吸烟量和可燃香烟依赖程度;(2)比较电子烟使用前后的总尼古丁使用频率(电子烟使用次数和每天吸烟量)和总尼古丁依赖程度;(3)研究尼古丁依赖的预测因素。

方法

我们使用了一项有 2896 名双用户的戒烟试验的基线数据。尼古丁使用频率和吸烟严重程度指数(Heaviness of Smoking Index)分别作为尼古丁使用和依赖的衡量标准。

结果

参与者每日吸烟量从吸烟前(M = 19.24,SD = 9.01)减少到吸烟后(M = 11.15,SD = 8.02,p <.0001),可燃香烟依赖程度从吸烟前(M = 3.55,SD = 1.51)减少到吸烟后(M = 2.11,SD = 1.60,p <.0001)。开始使用电子烟后,每日总尼古丁使用频率增加(M = 19.25,SD = 9.01 与 M = 29.46,SD = 8.61;p <.0001),总尼古丁依赖程度也增加(M = 3.55,SD = 1.51 与 M = 4.68,SD = 1.38;p <.0001)。分层回归分析表明,与总体尼古丁依赖程度较高相关的变量包括:年龄较小、教育程度较低、吸烟年限较长、吸烟前尼古丁依赖程度较高、每月使用电子烟天数较多、每次电子烟使用的吸气量较大、电子烟液尼古丁浓度较高、电子烟使用时间较长。

结论

双重使用会导致可燃香烟数量减少,但总尼古丁使用和依赖增加。

意义

在双重使用者中,电子烟使用开始后吸烟量减少可能会通过减少香烟摄入量来降低一些危害。然而,总尼古丁使用和依赖的增加可能会影响戒烟的能力,无论是戒掉一种还是两种产品。

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