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基于……叶提取物的银纳米颗粒的绿色合成及抗炎活性

Green Synthesis and Anti-Inflammatory Activity of Silver Nanoparticles Based on Leaves Extract of .

作者信息

Diallo Fatemata, Seck Insa, Ndoye Samba Fama, Niang Tamsir, Dieng Sidy Mouhamed, Thiam Fatou, Ndao Moussa, Sakho El Hadji Mamour, Fall Alioune, Séne Madièye, Seck Matar

机构信息

Laboratoire de Chimie de Coordination Organique et Bioorganique (LCCOB) Université Cheikh Anta DIOP de Dakar (UCAD), BP 5005 Dakar-Fann, Dakar, Senegal.

Laboratoire de Chimie Organique Chimie Physique et Chimie Thérapeutique Université Cheikh Anta DIOP de Dakar (UCAD), BP 5005 Dakar-Fann, Dakar, Senegal.

出版信息

Biochem Res Int. 2024 Sep 19;2024:3468868. doi: 10.1155/2024/3468868. eCollection 2024.

DOI:10.1155/2024/3468868
PMID:39345265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11427739/
Abstract

This study focuses on the synthesis of silver nanoparticles (AgNPs) using the extract of leaves. The extraction was done using maceration at room temperature in water for 48 h. The synthesized nanoparticles were characterized by IR, XRD, TEM, and SEM. The thermal stability of these nanoparticles was studied by TGA. The zeta potential was used to define the size, charge distribution, and stability of the nanoparticles. Optimization reactions were carried out based on reaction time, pH, and temperature. The nanoparticles obtained from optimal conditions were evaluated on induced inflammation. The determination of the average diameters and geometry of nanoparticles was carried out by XRD by calculating the lattice constants, and they are between 18.11 and 50 nm. The evaluation of anti-inflammatory activity showed that the nanoparticles are 10 times more active than the extract of leaves. Minimum doses of 10 mg/kg orally and 3 mg/kg were obtained for the plant extract, respectively. These results are promising for the possibility of AgNPs to be used for the treatment of inflammation.

摘要

本研究聚焦于利用树叶提取物合成银纳米颗粒（AgNPs）。提取过程是在室温下于水中采用浸渍法进行48小时。合成的纳米颗粒通过红外光谱（IR）、X射线衍射（XRD）、透射电子显微镜（TEM）和扫描电子显微镜（SEM）进行表征。通过热重分析（TGA）研究了这些纳米颗粒的热稳定性。zeta电位用于确定纳米颗粒的尺寸、电荷分布和稳定性。基于反应时间、pH值和温度进行了优化反应。对在最佳条件下获得的纳米颗粒进行了诱导炎症方面的评估。通过计算晶格常数，利用XRD测定了纳米颗粒的平均直径和几何形状，其直径在18.11至50纳米之间。抗炎活性评估表明，纳米颗粒的活性比树叶提取物高10倍。植物提取物口服的最小剂量分别为10毫克/千克和3毫克/千克。这些结果对于AgNPs用于治疗炎症的可能性而言很有前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d6e2a009d2ce/BRI2024-3468868.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d7856606b1a9/BRI2024-3468868.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/ad5d966687fb/BRI2024-3468868.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/542ec6f13213/BRI2024-3468868.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/718e712ddfef/BRI2024-3468868.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/047d988694a3/BRI2024-3468868.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/7f7bb87ae150/BRI2024-3468868.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d3d576d68103/BRI2024-3468868.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/09095228982d/BRI2024-3468868.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/9938acadaa22/BRI2024-3468868.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d6e2a009d2ce/BRI2024-3468868.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d7856606b1a9/BRI2024-3468868.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/ad5d966687fb/BRI2024-3468868.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/542ec6f13213/BRI2024-3468868.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/718e712ddfef/BRI2024-3468868.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/047d988694a3/BRI2024-3468868.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/7f7bb87ae150/BRI2024-3468868.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d3d576d68103/BRI2024-3468868.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/09095228982d/BRI2024-3468868.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/9938acadaa22/BRI2024-3468868.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9645/11427739/d6e2a009d2ce/BRI2024-3468868.010.jpg

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ACS Omega. 2022 Jan 5;7(2):1914-1933. doi: 10.1021/acsomega.1c05324. eCollection 2022 Jan 18.
2
Green synthesis of silver nanoparticles using plant leaf extract and their antibacterial and anti-oxidant activities.利用植物叶提取物绿色合成银纳米颗粒及其抗菌和抗氧化活性。
Heliyon. 2021 Nov 24;7(11):e08459. doi: 10.1016/j.heliyon.2021.e08459. eCollection 2021 Nov.
3
Biogenic Synthesis and Catalytic Efficacy of Silver Nanoparticles Based on Peel Extracts of Fruit.
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ACS Omega. 2021 Jul 9;6(28):18260-18268. doi: 10.1021/acsomega.1c02149. eCollection 2021 Jul 20.
4
The Antimicrobial and Anti-Inflammatory Effects of Silver Nanoparticles Synthesised from Aqueous Extract.水提取物合成的银纳米颗粒的抗菌和抗炎作用
Nanomaterials (Basel). 2021 May 20;11(5):1343. doi: 10.3390/nano11051343.
5
Antibacterial and wound healing-promoting effect of sponge-like chitosan-loaded silver nanoparticles biosynthesized by iturin.由伊枯草菌素生物合成的载银纳米海绵状壳聚糖的抗菌和促进伤口愈合作用。
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6
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J Immunotoxicol. 2019 Dec;16(1):63-73. doi: 10.1080/1547691X.2019.1588928.
9
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Front Microbiol. 2018 Jul 16;9:1555. doi: 10.3389/fmicb.2018.01555. eCollection 2018.
10
Green Synthesis of Metallic Nanoparticles via Biological Entities.通过生物实体实现金属纳米粒子的绿色合成
Materials (Basel). 2015 Oct 29;8(11):7278-7308. doi: 10.3390/ma8115377.