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中国老年帕金森病患者的营养状况

The Nutritional Status of Elderly Chinese Patients With Parkinson's Disease.

作者信息

Wu Sheng, Liu Peng, Tian Xiulin, Wang Bo, Ouyang Zhiyuan, Luo Wei

机构信息

Second Affiliated Hospital of Zhejiang University, Hangzhou, China.

Taizhou Central Hospital, China.

出版信息

Gerontol Geriatr Med. 2024 Sep 26;10:23337214241284181. doi: 10.1177/23337214241284181. eCollection 2024 Jan-Dec.

Abstract

To investigate the nutritional status of elderly Chinese patients with Parkinson's disease (PD) and analyze possible factors related to nutritional problems. Patients with PD aged 65 years or older were enrolled. Anthropometric assessment and Mini Nutritional Assessment were used to determine nutritional status. Various scales were completed to identify potentially related factors, such as Hoehn and Yahr stage (H&Y stage), 30 mL water swallow test, Clock Drawing Test (CDT), and Charlson Comorbidity Index (CCI). 785 patients were enrolled. The prevalence of malnutrition and risk of malnutrition was 3.1% (24/785) and 25.7% (202/785), respectively. Regression analyses indicated that H&Y stage ≥ 3 (OR: 2.151; 95%CI: 1.174-3.941;  = .013), abnormal water swallow test (OR: 4.559; 95%CI: 2.130-9.759;  < .001), CDT score < 6 (OR: 2.810; 95%CI: 1.534-5.148;  = .001), and CCI (OR: 1.621; 95%CI: 1.238-2.124;  < .001) were considered to be potential factors associated with low BMI. 28.8% of elderly PD patients were in abnormal nutritional status. Disease severity, dysphagia, cognitive function, and comorbidities might be related factors.

摘要

调查中国老年帕金森病(PD)患者的营养状况,并分析与营养问题相关的可能因素。纳入65岁及以上的PD患者。采用人体测量评估和微型营养评定法来确定营养状况。完成各种量表以识别潜在的相关因素,如Hoehn和Yahr分期(H&Y分期)、30毫升水吞咽试验、画钟试验(CDT)和Charlson合并症指数(CCI)。共纳入785例患者。营养不良和营养不良风险的患病率分别为3.1%(24/785)和25.7%(202/785)。回归分析表明,H&Y分期≥3(OR:2.151;95%CI:1.174 - 3.941;P = 0.013)、水吞咽试验异常(OR:4.559;95%CI:2.130 - 9.759;P < 0.001)、CDT评分<6(OR:2.810;95%CI:1.534 - 5.148;P = 0.001)和CCI(OR:1.621;95%CI:1.238 - 2.124;P < 0.001)被认为是与低体重指数相关的潜在因素。28.8%的老年PD患者营养状况异常。疾病严重程度、吞咽困难、认知功能和合并症可能是相关因素。

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