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辛丁-拉尔森-约翰森病。临床特征、影像学表现、保守治疗和研究展望:范围综述。

Sinding-Larsen-Johansson disease. Clinical features, imaging findings, conservative treatments and research perspectives: a scoping review.

机构信息

Department of Immunobiology and Environmental Microbiology, Medical University of Gdansk, Gdansk, Poland.

Medical University of Gdansk, Gdansk, Poland.

出版信息

PeerJ. 2024 Sep 25;12:e17996. doi: 10.7717/peerj.17996. eCollection 2024.

DOI:10.7717/peerj.17996
PMID:39346060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11438430/
Abstract

OBJECTIVE

This review aims to consolidate existing research on the pathogenesis, clinical diagnosis, imaging outcomes, and conservative treatments of Sinding-Larsen-Johansson disease (SLJD), identifying literature gaps.

DESIGN

Scoping Review.

METHODS

A comprehensive literature search was conducted across databases including PubMed, Scopus, Medline OVID, Embase, Web of Science, and Grey literature following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews. The quality of included studies was assessed using the Joanna Briggs Institute (JBI) checklist.

RESULTS

The body of evidence on SLJD, primarily derived from case studies, reveals limited and often conflicting data. Key findings include: (1) SLJD commonly presents as localized knee pain in physically active adolescents, particularly males, (2) ultrasound and MRI are the most effective diagnostic tools, (3) conservative treatment, which mainly focuses on activity limitation, yields positive outcomes within two to eight months.

CONCLUSIONS

Our review shows that SLJD mainly affects physically active adolescents aged 9-17 years. The authors recommend conservative treatment, rest and/or cryotherapy, passive mobilization, muscle restraint, isometric exercise, and NSAIDs. Further cohort studies are necessary to refine the management and application of the SLJD treatment database.

摘要

目的

本综述旨在整合 Sinding-Larsen-Johansson 病(SLJD)发病机制、临床诊断、影像学结果和保守治疗的现有研究,确定文献空白。

设计

范围综述。

方法

按照系统评价和荟萃分析的首选报告项目(PRISMA)扩展对范围综述进行全面的文献检索,涵盖 PubMed、Scopus、Medline OVID、Embase、Web of Science 和灰色文献数据库。使用 Joanna Briggs 研究所(JBI)清单评估纳入研究的质量。

结果

SLJD 的证据主要来自病例研究,结果表明数据有限且经常存在冲突。主要发现包括:(1)SLJD 通常表现为青少年,特别是男性,活跃的膝关节疼痛;(2)超声和 MRI 是最有效的诊断工具;(3)主要集中在活动限制的保守治疗在 2 至 8 个月内产生积极结果。

结论

我们的综述表明,SLJD 主要影响 9-17 岁的活跃青少年。作者建议采用保守治疗、休息和/或冷疗、被动运动、肌肉约束、等长运动和 NSAIDs。需要进一步的队列研究来完善 SLJD 治疗数据库的管理和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2e8/11438430/f26cb457e9aa/peerj-12-17996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2e8/11438430/f26cb457e9aa/peerj-12-17996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2e8/11438430/f26cb457e9aa/peerj-12-17996-g001.jpg

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