Uusitalo Maja, Strach Michal, Eriksson Gustav, Dmytrenko Tetiana, Andersson John, Dahlin Andreas, Hulander Mats, Andersson Martin
Department of Chemistry and Chemical Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden.
Chalmers Materials Analysis Laboratory, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden.
Nano Lett. 2024 Oct 9;24(40):12529-12535. doi: 10.1021/acs.nanolett.4c03472. Epub 2024 Sep 30.
Gold nanoparticles possess unique photothermal properties and have gained considerable interest in biomedical research, particularly for photothermal therapy (PTT). This study focuses on evaluating the photothermal properties of gold nanorods (AuNRs) supported on glass substrates upon excitation with near-infrared (NIR) light. Two aspect ratios of AuNRs were electrostatically immobilized onto glass with controlled coverage. X-ray diffraction (XRD) was performed to evaluate the photothermal behavior and morphological changes of the supported AuNRs during NIR laser irradiation. The XRD data sets were corroborated with scanning electron microscopy and Vis-NIR spectroscopy characterization. XRD revealed a linear temperature increase with laser power, aligning with theoretical predictions, and a slope dependent on the AuNR coverage, until the onset of morphology transformations around 120 °C. This study provides valuable insights into the photothermal properties of supported AuNRs, crucial for their application in PTT.
金纳米颗粒具有独特的光热性质，在生物医学研究中引起了广泛关注，尤其是在光热疗法（PTT）方面。本研究聚焦于评估负载在玻璃基板上的金纳米棒（AuNRs）在近红外（NIR）光激发下的光热性质。通过静电作用将两种长径比的AuNRs以可控的覆盖率固定在玻璃上。进行X射线衍射（XRD）以评估在近红外激光照射期间负载的AuNRs的光热行为和形态变化。XRD数据集通过扫描电子显微镜和可见-近红外光谱表征得到了证实。XRD显示温度随激光功率呈线性增加，这与理论预测一致，并且斜率取决于AuNRs的覆盖率，直到在约120°C时形态发生转变。本研究为负载的AuNRs的光热性质提供了有价值的见解，这对于它们在PTT中的应用至关重要。
