Department of Health Statistics, Naval Medical University, Shanghai, China.
School of Medicine, Tongji University, Shanghai, China.
J Med Internet Res. 2024 Sep 30;26:e58740. doi: 10.2196/58740.
Prehospital trauma triage is essential to get the right patient to the right hospital. However, the national field triage guidelines proposed by the American College of Surgeons have proven to be relatively insensitive when identifying severe traumas.
This study aimed to build a prehospital triage model to predict severe trauma and enhance the performance of the national field triage guidelines.
This was a multisite prediction study, and the data were extracted from the National Trauma Data Bank between 2017 and 2019. All patients with injury, aged 16 years of age or older, and transported by ambulance from the injury scene to any trauma center were potentially eligible. The data were divided into training, internal, and external validation sets of 672,309; 288,134; and 508,703 patients, respectively. As the national field triage guidelines recommended, age, 7 vital signs, and 8 injury patterns at the prehospital stage were included as candidate variables for model development. Outcomes were severe trauma with an Injured Severity Score ≥16 (primary) and critical resource use within 24 hours of emergency department arrival (secondary). The triage model was developed using an extreme gradient boosting model and Shapley additive explanation analysis. The model's accuracy regarding discrimination, calibration, and clinical benefit was assessed.
At a fixed specificity of 0.5, the model showed a sensitivity of 0.799 (95% CI 0.797-0.801), an undertriage rate of 0.080 (95% CI 0.079-0.081), and an overtriage rate of 0.743 (95% CI 0.742-0.743) for predicting severe trauma. The model showed a sensitivity of 0.774 (95% CI 0.772-0.776), an undertriage rate of 0.158 (95% CI 0.157-0.159), and an overtriage rate of 0.609 (95% CI 0.608-0.609) when predicting critical resource use, fixed at 0.5 specificity. The triage model's areas under the curve were 0.755 (95% CI 0.753-0.757) for severe trauma prediction and 0.736 (95% CI 0.734-0.737) for critical resource use prediction. The triage model's performance was better than those of the Glasgow Coma Score, Prehospital Index, revised trauma score, and the 2011 national field triage guidelines RED criteria. The model's performance was consistent in the 2 validation sets.
The prehospital triage model is promising for predicting severe trauma and achieving an undertriage rate of <10%. Moreover, machine learning enhances the performance of field triage guidelines.
创伤院前分诊对于将合适的患者送到合适的医院至关重要。然而,美国外科医师学院提出的国家现场分诊指南在识别严重创伤方面被证明相对不敏感。
本研究旨在建立一个院前分诊模型,以预测严重创伤,并提高国家现场分诊指南的性能。
这是一项多站点预测研究,数据来自于 2017 年至 2019 年的国家创伤数据库。所有年龄在 16 岁及以上、因受伤由救护车从受伤现场送往任何创伤中心的患者都有资格入组。数据被分为训练集、内部验证集和外部验证集,分别为 672309、288134 和 508703 例患者。根据国家现场分诊指南的建议,年龄、7 项生命体征和 8 种在院前阶段的损伤模式被纳入模型开发的候选变量。结局为损伤严重度评分≥16 分的严重创伤(主要结局)和急诊科到达后 24 小时内需要关键资源的患者(次要结局)。使用极端梯度提升模型和 Shapley 加法解释分析来开发分诊模型。评估了模型在区分度、校准度和临床获益方面的准确性。
在固定特异性为 0.5 时,模型对严重创伤的预测具有 0.799 的敏感性(95%CI 0.797-0.801)、0.080 的漏诊率(95%CI 0.079-0.081)和 0.743 的过度分诊率(95%CI 0.742-0.743)。模型对关键资源使用的预测具有 0.774 的敏感性(95%CI 0.772-0.776)、0.158 的漏诊率(95%CI 0.157-0.159)和 0.609 的过度分诊率(95%CI 0.608-0.609),特异性固定在 0.5。严重创伤预测的分诊模型曲线下面积为 0.755(95%CI 0.753-0.757),关键资源使用预测的曲线下面积为 0.736(95%CI 0.734-0.737)。分诊模型的性能优于格拉斯哥昏迷评分、院前指数、修订创伤评分和 2011 年国家现场分诊指南 RED 标准。该模型在两个验证集中的性能一致。
该院前分诊模型有望预测严重创伤,并实现<10%的漏诊率。此外,机器学习提高了现场分诊指南的性能。