Weill Cornell Medicine, New York, New York (R.M.G.).
National Institutes of Health, Bethesda, Maryland (A.K.P., R.R., H.M., H.C.L.).
Ann Intern Med. 2024 Nov;177(11):1547-1557. doi: 10.7326/ANNALS-24-00464. Epub 2024 Oct 1.
In March 2020, the White House Coronavirus Task Force determined that clinicians in the United States needed expert treatment guidelines to optimally manage patients with COVID-19, a potentially life-threatening disease caused by a new pathogen for which no specific treatments were known to be effective.
The U.S. Department of Health and Human Services requested that the National Institutes of Health (NIH) take the lead in expeditiously convening a panel of experts to create "living" guidelines that would be widely accessible and capable of frequent updating as important new information became available.
The purpose of this article is to expand on the experiences of the NIH COVID-19 Treatment Guidelines Panel (the Panel) over the past 4 years, summarize the Panel's final recommendations for COVID-19, highlight some challenges and unanswered questions about COVID-19 management, and inform future responses to public health emergencies. The Panel was formed in March 2020, and the first iteration of the guidelines was released in April 2020. Now that the public health emergency has ended, the NIH COVID-19 Treatment Guidelines have sunsetted. This role will now fall to professional societies and organizations, such as the American College of Physicians, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the World Health Organization, all of which have been active in this area.
2020 年 3 月，白宫冠状病毒特别工作组确定，美国临床医生需要专家治疗指南，以最佳方式管理 COVID-19 患者，这种疾病可能危及生命，由一种新病原体引起，目前已知没有有效的特定治疗方法。
美国卫生与公众服务部要求美国国立卫生研究院（NIH）牵头迅速召集一个专家组，制定“活”的指南，以便广泛获取，并能够在有重要新信息时频繁更新。
本文旨在扩大 NIH COVID-19 治疗指南专家组（专家组）在过去 4 年中的经验，总结专家组关于 COVID-19 的最终建议，突出 COVID-19 管理方面的一些挑战和未解决的问题，并为未来应对公共卫生紧急情况提供信息。专家组于 2020 年 3 月成立，指南的第一个版本于 2020 年 4 月发布。随着公共卫生紧急情况的结束，NIH COVID-19 治疗指南已经结束。这一角色现在将由专业协会和组织承担，如美国医师学院、美国传染病学会、儿科传染病学会和世界卫生组织，它们在这一领域一直很活跃。
