Kofoed H, Sjøntoft E, Siemssen S O, Olesen H P
Acta Orthop Scand. 1985 Oct;56(5):400-3. doi: 10.3109/17453678508994357.
We investigated the immediate effect of osteotomy of the femoral shaft in adult dogs on intramedullary pO2, pCO2, relative bone blood flow (RBF) and intraosseous pressure (IOP). Single osteotomy resulted in a pO2 decrease from 49 mm Hg to 30 mm Hg. Double osteotomy further reduced pO2 to 21 mm Hg. Following double osteotomy, pCO2 increased from 42 mm Hg to 55 mm Hg. IOP was decreased by single osteotomy from 29 mm Hg to 15 mm Hg, and to 4 mm Hg by the second osteotomy. Linear regression analysis showed a negative correlation between pCO2 and RBF. We concluded that osteotomy introduces immediate haemodynamic and metabolic changes in the bone marrow canal. A periosteal supply of the endosteal bone seems possible provided this system is intact.
我们研究了成年犬股骨干截骨术对骨髓内氧分压（pO2）、二氧化碳分压（pCO2）、相对骨血流量（RBF）和骨内压（IOP）的即时影响。单次截骨导致pO2从49毫米汞柱降至30毫米汞柱。二次截骨进一步将pO2降至21毫米汞柱。二次截骨后，pCO2从42毫米汞柱升至55毫米汞柱。单次截骨使IOP从29毫米汞柱降至15毫米汞柱，二次截骨后降至4毫米汞柱。线性回归分析显示pCO2与RBF之间呈负相关。我们得出结论，截骨术会立即引起骨髓腔内血液动力学和代谢变化。只要骨膜系统完整，骨内膜骨的骨膜血供似乎是可能的。
