Department of Food and Nutrition, College of Bionanotechnology, Gachon University, Seongnam-si 13120, Gyeonggi-do, Republic of Korea.
Department of Food and Nutrition, College of Bionanotechnology, Gachon University, Seongnam-si 13120, Gyeonggi-do, Republic of Korea; Institute for Aging and Clinical Nutrition Research, Gachon University, Seongnam-si 13120, Gyeonggi-do, Republic of Korea.
Int J Biol Macromol. 2024 Nov;281(Pt 2):135536. doi: 10.1016/j.ijbiomac.2024.135536. Epub 2024 Sep 30.
Exopolysaccharides (EPSs) from lactic acid bacteria (LAB) have multifunctional capabilities owing to their diverse structural conformations, monosaccharide compositions, functional groups, and molecular weights. A review paper on EPS production and antioxidant potential of different LAB genera has not been thoroughly reviewed. Therefore, the current review provides comprehensive information on the biosynthesis of EPSs, including the isolation source, type, characterization techniques, and application, with a primary focus on their antioxidant potential. According to this review, 17 species of Lactobacillus, five species of Bifidobacterium, four species of Leuconostoc, three species of Weissella, Enterococcus, and Lactococcus, two species of Pediococcus, and one Streptococcus species have been documented to exhibit antioxidant activity. Of the 111 studies comprehensively reviewed, 98 evaluated the radical scavenging activity of EPSs through chemical-based assays, whereas the remaining studies documented the antioxidant activity using cell and animal models. Studies have shown that different LAB genera have a unique capacity to produce homo- (HoPs) and heteropolysaccharides (HePs), with varied carbohydrate compositions, linkages, and molecular weights. Leuconostoc, Weissella, and Pediococcus were the main HoPs producers, whereas the remaining genera were the main HePs producers. Recent trends in EPSs production and blending to improve their properties have also been discussed.
乳酸菌（LAB）的胞外多糖（EPSs）由于其多样的结构构象、单糖组成、官能团和分子量，具有多功能特性。关于不同 LAB 属的 EPS 生产和抗氧化潜力的综述文章尚未得到彻底审查。因此，本综述提供了关于 EPS 生物合成的综合信息，包括分离来源、类型、表征技术和应用，主要关注其抗氧化潜力。根据这篇综述，已经有 17 种乳杆菌、5 种双歧杆菌、4 种肠膜明串珠菌、3 种魏斯氏菌、肠球菌和乳球菌、2 种乳酸片球菌和 1 种链球菌被记录具有抗氧化活性。在全面审查的 111 项研究中，有 98 项通过基于化学的测定评估了 EPS 的自由基清除活性，而其余研究则使用细胞和动物模型记录了抗氧化活性。研究表明，不同的 LAB 属具有产生同型（HoPs）和异多糖（HePs）的独特能力，具有不同的碳水化合物组成、键合和分子量。肠膜明串珠菌、魏斯氏菌和乳酸片球菌是主要的 HoPs 产生菌，而其余属是主要的 HePs 产生菌。还讨论了 EPSs 生产和混合以改善其性能的最新趋势。
