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一名金匠的急性氰化物中毒及急救处理:病例报告

Acute Cyanide Toxicity and Emergency Management in a Goldsmith: A Case Report.

作者信息

Ponaganti Mythily Rao, Tudi Pavan

机构信息

Internal Medicine, KIMS (Krishna Institute of Medical Sciences) Sunshine Superspeciality Hospital, Hyderabad, IND.

出版信息

Cureus. 2024 Aug 30;16(8):e68254. doi: 10.7759/cureus.68254. eCollection 2024 Aug.

DOI:10.7759/cureus.68254
PMID:39350829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11440009/
Abstract

Acute cyanide toxicity is very rare but it is almost always associated with fatal outcomes. Here we describe the case of a 43-year-old healthy male who worked in a jewelry factory and presented with acute cyanide toxicity. He was successfully managed with all the supportive measures and an appropriate antidote kit containing amyl nitrite, sodium nitrite, and sodium thiosulfate. We also describe the relevant importance of knowing the history of easy access to cyanide as a part of the patient's profession, the critical nature of the patient at presentation, as well as the efforts needed to procure the antidote.

摘要

急性氰化物中毒非常罕见,但几乎总是与致命后果相关。在此,我们描述一名43岁健康男性的病例,他在一家珠宝厂工作,出现了急性氰化物中毒。通过所有支持措施以及包含亚硝酸异戊酯、亚硝酸钠和硫代硫酸钠的适当解毒剂套件,他得到了成功救治。我们还描述了了解患者职业中容易接触氰化物的病史的相关重要性、患者就诊时的危急状况以及获取解毒剂所需的努力。

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本文引用的文献

1
Accidental Deaths Due to Toxic Industrial Cyanide Inhalation: An Autopsy Case Report.因吸入工业有毒氰化物导致的意外死亡:一例尸检病例报告
Cureus. 2022 May 26;14(5):e25376. doi: 10.7759/cureus.25376. eCollection 2022 May.
2
A Review on Ingested Cyanide: Risks, Clinical Presentation, Diagnostics, and Treatment Challenges.摄入氰化物综述:风险、临床特征、诊断和治疗挑战。
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Challenges in the diagnosis of acute cyanide poisoning.急性氰化物中毒诊断中的挑战。
Clin Toxicol (Phila). 2018 Jul;56(7):609-617. doi: 10.1080/15563650.2018.1435886. Epub 2018 Feb 8.
4
Accidental Ingestion of Traces of Cyanide: A Clinical Experience.意外摄入微量氰化物:临床经验
Indian J Crit Care Med. 2017 Nov;21(11):804-805. doi: 10.4103/ijccm.IJCCM_288_17.
5
Acute cyanide Intoxication: A rare case of survival.急性氰化物中毒:一例罕见的存活病例。
Indian J Anaesth. 2014 May;58(3):312-4. doi: 10.4103/0019-5049.135045.
6
Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation.羟钴胺用于治疗因摄入或吸入导致的严重急性氰化物中毒。
Am J Emerg Med. 2007 Jun;25(5):551-8. doi: 10.1016/j.ajem.2006.10.010.
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Cyanide: critical issues in diagnosis and treatment.氰化物:诊断与治疗中的关键问题
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Antidotal treatment of cyanide poisoning.氰化物中毒的解毒治疗。
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Acute cyanide intoxication treated with a combination of hydroxycobalamin, sodium nitrite, and sodium thiosulfate.采用羟钴胺素、亚硝酸钠和硫代硫酸钠联合治疗急性氰化物中毒。
J Toxicol Clin Toxicol. 2002;40(2):181-3. doi: 10.1081/clt-120004408.
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Why are so many food plants cyanogenic?为什么有这么多食用植物含氰?
Phytochemistry. 1998 Jan;47(2):155-62. doi: 10.1016/s0031-9422(97)00425-1.