Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Front Endocrinol (Lausanne). 2024 Sep 16;15:1403087. doi: 10.3389/fendo.2024.1403087. eCollection 2024.
Although radiofrequency ablation (RFA) is a safe and effective non-surgical treatment for benign thyroid nodules, injury to the recurrent laryngeal nerve (RLN), is a potential and feared complication. Intermittent voice checks have been proposed to monitor vocal cord (VC) function during RFA, but such assessment is highly subjective and effort-dependent.
We are here reporting the methodological use of flexible laryngoscopy (FL) for VC monitoring during bilateral thyroid RFA treatment. The patient, a 35-year-old woman, was referred to the Endocrinology Unit for subclinical hyperthyroidism due to bilateral autonomously functioning thyroid nodules.
At the end of the treatment of the first nodule, the FL performed by an otorhinolaryngologist specialist allowed evaluating VC function and ruling out possible paralysis before proceeding with the contralateral RFA treatment. The patient was awake during the entire procedure and well tolerated the laryngoscopic examination. The TSH serum evaluations performed one month and 9 months after the procedure assessed an euthyroid state (TSH 3.2 mIU/L and 2.8 mIU/L, respectively).
During bilateral thyroid RFA the use of FL for VC monitoring treatment resulted in a safe, easy-to-perform, and effective strategy to minimize and anticipate RLN injury risk in the awake patient. The prevention of RLN damage is advisable in the case of single RFA treatment, while it should be strongly recommended when RFA is performed on bilateral nodules.
射频消融 (RFA) 是治疗良性甲状腺结节的一种安全有效的非手术治疗方法,但损伤喉返神经 (RLN) 是一种潜在且令人恐惧的并发症。间歇性嗓音检查已被提议用于监测 RFA 过程中的声带 (VC) 功能,但这种评估高度依赖于主观判断和努力程度。
我们在此报告了在双侧甲状腺 RFA 治疗过程中使用纤维喉镜 (FL) 监测 VC 的方法学应用。该患者为 35 岁女性,因双侧自主功能性甲状腺结节导致亚临床甲状腺功能亢进症被转诊至内分泌科。
在第一个结节的治疗结束时,耳鼻喉科专家进行的 FL 检查允许评估 VC 功能,并在进行对侧 RFA 治疗之前排除可能的麻痹。患者在整个过程中保持清醒,并且能够很好地耐受喉镜检查。在术后一个月和 9 个月进行的 TSH 血清评估显示甲状腺功能处于正常状态(TSH 分别为 3.2 mIU/L 和 2.8 mIU/L)。
在双侧甲状腺 RFA 中,使用 FL 监测 VC 治疗是一种安全、易于实施且有效的策略,可以最大限度地降低和预测清醒患者 RLN 损伤的风险。在进行单次 RFA 治疗时,建议预防 RLN 损伤,而在双侧结节进行 RFA 时,则应强烈推荐。