Li Aoshuang, Zhang Mingyang, Ning Bin
Department of Cardiology, Fuyang People's Hospital, Anhui Medical University, 236000, Fuyang, China.
J Cardiothorac Surg. 2024 Oct 1;19(1):552. doi: 10.1186/s13019-024-03070-6.
Although patients with paroxysmal atrial fibrillation (PAF) are preferred to undergo catheter ablation (CA), the high possibility of recurrence following surgery is still concerning. We aimed to evaluate the ability of the left atrioventricular coupling index (LACI), which is the ratio of the left atrium end-diastolic volume to the left ventricle end-diastolic volume, to predict PAF recurrence after CA.
Patients with PAF undergoing CA for the first time between January 2018 and June 2021 were admitted and grouped by recurrence within a year. LACI was measured before CA using ultrasonography. Risk factors identified by multivariable logistic regression analysis, and the area under the receiver operating characteristic (ROC) curve was used to assess the ability of LACI to predict PAF recurrence after CAP.
Among the 204 patients treated at our hospital, 164 patients were included in the research after eliminating those who were lost to follow-up. Among them, 56 individuals had recurrence following a 90-day blanking period. Recurrence is more likely in elderly patients with high blood pressure. Patients who suffered recurrence exhibited lower left atrial ejection fraction and increased LACI, left atrial volume minimum, and left atrium volume index maximum. LACI was an independent risk factor for postoperative recurrence (OR: 1.526, 95% CI: 1.325-1.757, P < 0.001), and ROC displayed remarkable predictive value [area under the curve (AUC) = 0.868].
High LACI is significantly associated with postoperative recurrence in PAF patients, and LACI has incremental prognostic value to predict recurrence.
尽管阵发性心房颤动(PAF)患者首选进行导管消融(CA),但术后复发的高可能性仍然令人担忧。我们旨在评估左房室耦合指数(LACI,即左心房舒张末期容积与左心室舒张末期容积之比)预测CA术后PAF复发的能力。
纳入2018年1月至2021年6月首次接受CA的PAF患者,并按1年内的复发情况进行分组。在CA术前使用超声心动图测量LACI。通过多变量逻辑回归分析确定危险因素,并使用受试者操作特征(ROC)曲线下面积评估LACI预测CAP术后PAF复发的能力。
在我院接受治疗的204例患者中,排除失访患者后,164例患者纳入研究。其中,56例在90天空白期后出现复发。老年高血压患者更容易复发。复发患者表现出较低的左心房射血分数,以及升高的LACI、左心房最小容积和左心房最大容积指数。LACI是术后复发的独立危险因素(OR:1.526,95%CI:1.325-1.757,P < 0.001),ROC显示出显著的预测价值[曲线下面积(AUC)=0.868]。
高LACI与PAF患者术后复发显著相关,且LACI对预测复发具有递增的预后价值。