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基孔肯雅热所致慢性病对生活质量和功能的影响。

Impact of chronic illness caused by chikungunya fever on quality of life and functionality.

作者信息

Dutra Jéssica Isabelle Santos, Souza Marcelo Cardoso de, Lins Caio Alano Almeida, Medeiros Anna Cecília Queiroz de

机构信息

Faculdade de Ciências da Saúde do Trairi, Universidade Federal do Rio Grande do Norte, Santa Cruz, RN, Brazil.

Department of Physiotherapy, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

出版信息

Einstein (Sao Paulo). 2024 Sep 30;22:eAO0562. doi: 10.31744/einstein_journal/2024AO0562. eCollection 2024.

Abstract

BACKGROUND

Chikungunya fever compromises the functionality and quality of life in the affected individuals, even one year after the acute phase of the disease. Chronically affected people experience direct impairment in performing daily activities, along with a risk of developing other morbidities.

BACKGROUND

◼ Even after a year, chikungunya fever-affected people experience damage to their physical and mental health.

BACKGROUND

◼ Positive screening for depression risk was 13.5 times more likely in chronically affected.

BACKGROUND

◼ Patients with chronic chikungunya fever had a 76 times higher risk of walking impairments.

OBJECTIVE

To evaluate the impact of chronic illness caused by chikungunya fever on the quality of life and functionality of affected individuals.

METHODS

A cross-sectional and comparative study was conducted in which two groups were investigated: a Chikungunya Group comprising 25 patients with chronic fever screened after 1 year of illness via a telephonic survey, and a Healthy Group comprising 25 healthy individuals matched for sex and age by face-to-face interview. The Stanford HAQ 20-Item Disability Scale (HAQ) and the Short Form Health Survey (SF-12) questionnaires were administered to both groups. Generalized Linear Models, Pearson χ2 tests, and odds ratios were used to evaluate the test results.

RESULTS

Significant differences in functional capacity and quality of life were observed between the Chikungunya and Healthy Groups. The chance of some impairment in functionality was also much higher in the Chikungunya Group in four of the HAQ categories, especially in the "walking" category (adjusted OR= 109.40). Further, the Chikungunya Group had a higher chance of presenting a below-average score in the mental component summary of the SF-12 (adjusted OR= 16.20) and of being positive in depression risk screening (adjusted OR= 34.57).

CONCLUSION

Even one year after the acute phase, chikungunya fever can compromise the functionality and quality of life in affected individuals, with direct impairment in performing daily activities. Studies and therapeutic plans for chikungunya fever should consider the long-term impacts of this disease.

摘要

背景

基孔肯雅热会损害患者的功能和生活质量,即使在疾病急性期过后一年也是如此。长期患病的人在进行日常活动时会直接受到影响,同时还存在患上其他疾病的风险。

背景

◼ 即使在一年后,感染基孔肯雅热的人仍会经历身心健康受损。

背景

◼ 长期患病者患抑郁症风险的阳性筛查可能性要高13.5倍。

背景

◼ 慢性基孔肯雅热患者行走障碍的风险要高76倍。

目的

评估基孔肯雅热导致的慢性病对患者生活质量和功能的影响。

方法

进行了一项横断面比较研究,调查了两组:基孔肯雅热组,通过电话调查对25名患病1年后的慢性发热患者进行筛查;健康组,通过面对面访谈选取25名年龄和性别匹配的健康个体。对两组均采用斯坦福健康评估问卷20项残疾量表(HAQ)和简短健康调查问卷(SF - 12)。使用广义线性模型、Pearson χ2检验和比值比来评估测试结果。

结果

基孔肯雅热组和健康组在功能能力和生活质量方面存在显著差异。在HAQ的四个类别中,基孔肯雅热组出现某种功能障碍的可能性也高得多,尤其是在“行走”类别(调整后的比值比 = 109.40)。此外,基孔肯雅热组在SF - 12的心理成分总结中得分低于平均水平的可能性更高(调整后的比值比 = 16.20),且抑郁症风险筛查呈阳性的可能性更高(调整后的比值比 = 34.57)。

结论

即使在急性期过后一年,基孔肯雅热仍会损害患者的功能和生活质量,在进行日常活动时会直接受到影响。针对基孔肯雅热的研究和治疗方案应考虑该疾病的长期影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce75/11461011/53ab3e302533/2317-6385-eins-22-eAO0562-gf02.jpg

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