Freelance Journalist, Berlin, Germany.
Biomed J. 2024 Oct;47(5):100792. doi: 10.1016/j.bj.2024.100792. Epub 2024 Sep 30.
This issue of the Biomedical Journal features a special section on extracellular vesicles (EVs), covering their role in neurological diseases, viral infections, trogocytosis, allogeneic organ rejection and tolerance, as well as EV biodistribution. Two articles explore the mechanisms of Parkinson's disease, focusing on white matter and exosomes. This journal issue also examines polyomavirus-induced damage in renal transplant grafts, proposes a miRNA signature as a diagnostic biomarker for Kawasaki disease, discusses neural gating and associated brain wave alterations, and further clarifies the relationship between gut microbiota and immune checkpoint inhibitors. Additionally, the importance of therapeutic drug monitoring is reaffirmed.
本期《生物医学期刊》设有一个关于细胞外囊泡 (EVs) 的特别版块，涵盖了它们在神经疾病、病毒感染、trogoctosis、同种异体器官排斥和耐受以及 EV 生物分布中的作用。两篇文章探讨了帕金森病的发病机制，重点关注了白质和外泌体。本期期刊还研究了多瘤病毒引起的肾移植移植物损伤，提出了 miRNA 特征作为川崎病的诊断生物标志物，讨论了神经门控和相关脑电波改变，并进一步阐明了肠道微生物群与免疫检查点抑制剂之间的关系。此外，还重申了治疗药物监测的重要性。
