Ramezanzade Elham, Khosravi Masoud, Jafarinezhad Alireza, Sadeghi Dehbane Sepideh, Attarchi Mirsaeed
Razi Clinical Research Development Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Caspian J Intern Med. 2024 Sep 7;15(4):682-689. doi: 10.22088/cjim.15.4.682. eCollection 2024 Fall.
Sleep disorders frequently affect end-stage renal disease patients on dialysis. However, the relationship between sleep quality and residual kidney function is still unclear. Therefore, this study aimed to investigate this relationship.
In this analytical cross-sectional study, 225 patients who were referred to dialysis centers were studied, and based on renal function, they were classified into two groups with and without residual kidney function. The study employed the Pittsburgh Sleep Quality Index questionnaire to evaluate sleep quality. Multiple linear regression was utilized to determine the factors affecting sleep quality with a significance level consideration at p<0.05.
The mean age of patients was 58.23 ± 13.50 years. 58.7% of patients were males. The problem of serious and very serious sleep in the Sleep latency and sleep duration has been more than other components. 72% of hemodialysis patients had poor sleep quality. In the multiple linear regression model, age (β = 0.442, 95% CI: 0.096, 0.788), sex (β = -0.847, 95% CI: -1.641, -0.054), Body mass index (β = 0.153, 95% CI: 0.058, 0.249) and dialysis duration (β = 0.097, 95% CI: 0.002, 0.192) were independently and significantly associated with sleep quality score. However, there was no statistically significant relationship between sleep quality and residual kidney function.
In conclusion, poor sleep quality is very common in patients undergoing hemodialysis. Therefore, sleep disorders in hemodialysis patients should be considered as one of the most challenging problems by healthcare providers, and early diagnosis and intervention are essential to improve sleep quality.
睡眠障碍经常影响接受透析的终末期肾病患者。然而，睡眠质量与残余肾功能之间的关系仍不明确。因此，本研究旨在调查这种关系。
在这项分析性横断面研究中，对225名转诊至透析中心的患者进行了研究，并根据肾功能将他们分为有残余肾功能和无残余肾功能两组。该研究采用匹兹堡睡眠质量指数问卷来评估睡眠质量。运用多元线性回归来确定影响睡眠质量的因素，显著性水平设定为p<0.05。
患者的平均年龄为58.23±13.50岁。58.7%的患者为男性。睡眠潜伏期和睡眠时间方面严重和非常严重的睡眠问题比其他部分更多。72%的血液透析患者睡眠质量较差。在多元线性回归模型中，年龄（β = 0.442，95%置信区间：0.096，0.788）、性别（β = -0.847，95%置信区间：-1.641，-0.054）、体重指数（β = 0.153，95%置信区间：0.058，0.249）和透析时间（β = 0.097，95%置信区间：0.002，0.192）与睡眠质量评分独立且显著相关。然而，睡眠质量与残余肾功能之间没有统计学上的显著关系。
总之，睡眠质量差在接受血液透析的患者中非常普遍。因此，医疗服务提供者应将血液透析患者的睡眠障碍视为最具挑战性的问题之一，早期诊断和干预对于改善睡眠质量至关重要。
