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Application of Artificial Intelligence in Ophthalmology: An Updated Comprehensive Review.

作者信息

Hashemian Hesam, Peto Tunde, Ambrósio Renato, Lengyel Imre, Kafieh Rahele, Muhammed Noori Ahmed, Khorrami-Nejad Masoud

机构信息

Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

School of Medicine, Dentistry and Biomedical Sciences, Centre for Public Health, Queen's University Belfast, Northern Ireland, UK.

出版信息

J Ophthalmic Vis Res. 2024 Sep 16;19(3):354-367. doi: 10.18502/jovr.v19i3.15893. eCollection 2024 Jul-Sep.


DOI:10.18502/jovr.v19i3.15893
PMID:39359529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11444002/
Abstract

Artificial intelligence (AI) holds immense promise for transforming ophthalmic care through automated screening, precision diagnostics, and optimized treatment planning. This paper reviews recent advances and challenges in applying AI techniques such as machine learning and deep learning to major eye diseases. In diabetic retinopathy, AI algorithms analyze retinal images to accurately identify lesions, which helps clinicians in ophthalmology practice. Systems like IDx-DR (IDx Technologies Inc, USA) are FDA-approved for autonomous detection of referable diabetic retinopathy. For glaucoma, deep learning models assess optic nerve head morphology in fundus photographs to detect damage. In age-related macular degeneration, AI can quantify drusen and diagnose disease severity from both color fundus and optical coherence tomography images. AI has also been used in screening for retinopathy of prematurity, keratoconus, and dry eye disease. Beyond screening, AI can aid treatment decisions by forecasting disease progression and anti-VEGF response. However, potential limitations such as the quality and diversity of training data, lack of rigorous clinical validation, and challenges in regulatory approval and clinician trust must be addressed for the widespread adoption of AI. Two other significant hurdles include the integration of AI into existing clinical workflows and ensuring transparency in AI decision-making processes. With continued research to address these limitations, AI promises to enable earlier diagnosis, optimized resource allocation, personalized treatment, and improved patient outcomes. Besides, synergistic human-AI systems could set a new standard for evidence-based, precise ophthalmic care.

摘要

相似文献

[1]
Application of Artificial Intelligence in Ophthalmology: An Updated Comprehensive Review.

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[2]
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引用本文的文献

[1]
Artificial Intelligence Improves Patient Follow-Up in a Diabetic Retinopathy Screening Program [Letter].

Clin Ophthalmol. 2025-8-9

[2]
Emerging innovations in ophthalmic drug delivery for diabetic retinopathy: a translational perspective.

Drug Deliv Transl Res. 2025-7-20

[3]
Comparing No-Code Platforms and Deep Learning Models for Glaucoma Detection From Fundus Images.

Cureus. 2025-3-24

[4]
Lights and Shadows on Artificial Intelligence in Glaucoma: Transforming Screening, Monitoring, and Prognosis.

J Clin Med. 2025-3-21

[5]
Prediction of the Cause of Fundus-Obscuring Vitreous Hemorrhage Using Machine Learning.

Diagnostics (Basel). 2025-2-4

[6]
Strategies for Early Keratoconus Diagnosis: A Narrative Review of Evaluating Affordable and Effective Detection Techniques.

J Clin Med. 2025-1-13

[7]
A comparative study of GPT-4o and human ophthalmologists in glaucoma diagnosis.

Sci Rep. 2024-12-5

本文引用的文献

[1]
Evaluation of OCT biomarker changes in treatment-naive neovascular AMD using a deep semantic segmentation algorithm.

Eye (Lond). 2024-11

[2]
Recent Advances in Imaging Macular Atrophy for Late-Stage Age-Related Macular Degeneration.

Diagnostics (Basel). 2023-12-10

[3]
Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features.

Invest Ophthalmol Vis Sci. 2023-10-3

[4]
Deep learning visual field global index prediction with optical coherence tomography parameters in glaucoma patients.

Sci Rep. 2023-10-25

[5]
Machine Learning to Predict Faricimab Treatment Outcome in Neovascular Age-Related Macular Degeneration.

Ophthalmol Sci. 2023-8-18

[6]
Maintenance of Vision Needed to Drive after Intravitreal Anti-VEGF Therapy in Patients with Neovascular Age-related Macular Degeneration and Diabetic Macular Edema.

Ophthalmol Retina. 2024-4

[7]
Artificial intelligence and deep learning in ophthalmology: Current status and future perspectives.

Adv Ophthalmol Pract Res. 2022-8-24

[8]
Diagnostic Accuracy of Automated Diabetic Retinopathy Image Assessment Softwares: IDx-DR and Medios Artificial Intelligence.

Ophthalmic Res. 2023

[9]
Glaucoma: now and beyond.

Lancet. 2023-11-11

[10]
Revolutionizing healthcare: the role of artificial intelligence in clinical practice.

BMC Med Educ. 2023-9-22

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