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蜂蜇伤的临床并发症:对发病机制、诊断和药物干预的深入了解。

Clinical complications in envenoming by honeybee stings: insights into mechanisms, diagnosis, and pharmacological interventions.

机构信息

Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.

Department of Bioprocess and Biotechnology, School of Agriculture, Agronomic Sciences School, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.

出版信息

Front Immunol. 2024 Sep 18;15:1437413. doi: 10.3389/fimmu.2024.1437413. eCollection 2024.

Abstract

Envenoming resulting from honeybee stings pose a neglected public health concern, with clinical complications ranging from mild local reactions to severe systemic manifestations. This review explores the mechanisms underlying envenoming by honeybee sting, discusses diagnostic approaches, and reviews current pharmacological interventions. This section explores the diverse clinical presentations of honeybee envenoming, including allergic and non-allergic reactions, emphasizing the need for accurate diagnosis to guide appropriate medical management. Mechanistic insights into the honeybee venom's impact on physiological systems, including the immune and cardiovascular systems, are provided to enhance understanding of the complexities of honeybee sting envenoming. Additionally, the article evaluates emerging diagnostic technologies and therapeutic strategies, providing a critical analysis of their potential contributions to improved patient outcomes. This article aims to provide current knowledge for healthcare professionals to effectively manage honeybee sting envenoming, thereby improving patient care and treatment outcomes.

摘要

蜜蜂蜇伤导致的中毒是一个被忽视的公共卫生问题,其临床并发症从轻度局部反应到严重全身表现不等。本文探讨了蜜蜂蜇伤中毒的机制,讨论了诊断方法,并综述了目前的药理学干预措施。本节探讨了蜜蜂蜇伤的多种临床表现,包括过敏和非过敏反应,强调了准确诊断以指导适当的医疗管理的必要性。本文提供了对蜜蜂毒液对生理系统(包括免疫系统和心血管系统)影响的机制见解,以增强对蜜蜂蜇伤中毒复杂性的理解。此外,文章还评估了新兴的诊断技术和治疗策略,批判性地分析了它们对改善患者结局的潜在贡献。本文旨在为医疗保健专业人员提供有关有效管理蜜蜂蜇伤中毒的最新知识,从而改善患者的护理和治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2550/11445026/6ef84450fc6b/fimmu-15-1437413-g001.jpg

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