Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria 3052, Australia
Genes Dev. 2024 Oct 16;38(17-20):820-822. doi: 10.1101/gad.352292.124.
Solid tumors that arise in the body interact with neurons, which influences cancer progression and treatment response. Here, we discuss key questions in the field, including defining the nature of interactions between tumors and neural circuits and defining how neural signals shape the tumor microenvironment. This information will allow us to optimally target neural signaling to improve outcomes for cancer patients.
体内发生的实体肿瘤与神经元相互作用，这影响着癌症的进展和治疗反应。在这里，我们讨论了该领域的关键问题，包括定义肿瘤和神经回路之间相互作用的性质以及定义神经信号如何塑造肿瘤微环境。这些信息将使我们能够优化靶向神经信号的治疗方法，从而改善癌症患者的治疗效果。
