Department of Pathology, New York University Grossman School of Medicine, New York, New York 10016, USA.
Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, New York 10016, USA.
Genes Dev. 2024 Oct 16;38(17-20):814-816. doi: 10.1101/gad.352300.124.
Recent work has highlighted the central role the brain-body axis plays in not only maintaining organismal homeostasis but also coordinating the body's response to immune and inflammatory insults. Here, we discuss how science is poised to address the many ways that our brain is directly involved with disease. In particular, we feel that combining cutting-edge tools in neuroscience with translationally relevant models of cancer will be critical to understanding how the brain and tumors communicate and modulate each other's behavior.
最近的研究强调了脑-体轴在维持机体稳态以及协调机体对免疫和炎症损伤的反应方面的核心作用。在这里，我们讨论科学如何解决我们的大脑直接参与疾病的许多方式。特别是，我们认为将神经科学的尖端工具与癌症的转化相关模型相结合对于理解大脑和肿瘤如何相互沟通以及调节彼此的行为至关重要。
