Department of Cosmetology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Affiliated Zhejiang Chinese Medical University, Wenzhou, Zhejiang, China.
Skin Res Technol. 2024 Oct;30(10):e70091. doi: 10.1111/srt.70091.
Facial photoaging is a type of facial skin aging induced mainly by exogenous factors (ultraviolet radiation) and often manifests itself in the form of hyperpigmentation, telangiectasia, roughness, increase in fine lines/wrinkles, and enlarged pores. Recently, picosecond lasers have become an emerging option for the treatment of facial photoaging, and long-pulse alexandrite lasers (LPAL) have demonstrated promising potential in the treatment of photoaging-related symptoms. This study aimed to evaluate the efficacy and safety of picosecond alexandrite laser (PSAL) with diffractive lens array (DLA) combined with LPAL for facial photoaging.
This is a retrospective study of 20 Chinese female patients with facial photoaging who received PSAL with DLA combined with LPAL during a 1-year period. All patients were treated every 4 weeks for a total of three treatments. Objective indicators of facial photoaging and patient satisfaction were evaluated before each treatment, and pain scores and adverse effects were recorded after each treatment.
Compared with baseline, patients showed significant differences in all facial photoaging indices (p < 0.01). After receiving three treatments, there was a 20.1% decrease in the pigmentation index, a 23.9% decrease in the erythema index, a 34.5% decrease in the texture index, a 28.4% decrease in the fine lines index, a 56% decrease in the pore index, a 9.3% elevation and a 17.1% decrease in elasticity R2 and F4, respectively, and a 55% decrease in sebum content. The mean satisfaction score for the three treatments was 4.67 (3.33, 5.00), and the mean visual analogue scale (VAS) pain score was 7.00. No serious adverse effects such as post-inflammatory hyperpigmentation (PIH), hypopigmentation, or blistering were observed at the treatment site during the treatment period.
PSAL with DLA combined with LPAL for the treatment of facial photoaging with significant efficacy, high patient satisfaction, and minimal adverse effects.
面部光老化是一种主要由外源性因素（紫外线辐射）引起的面部皮肤老化，其表现形式通常为色素沉着过度、毛细血管扩张、粗糙、细纹/皱纹增加、毛孔增大。近年来，皮秒激光已成为治疗面部光老化的一种新兴选择，长脉冲翠绿宝石激光（LPAL）在治疗光老化相关症状方面显示出了很大的潜力。本研究旨在评估皮秒倍频翠绿宝石激光（PSAL）联合长脉冲翠绿宝石激光（LPAL）治疗面部光老化的疗效和安全性。
这是一项回顾性研究，纳入了 20 名接受皮秒倍频翠绿宝石激光联合长脉冲翠绿宝石激光治疗的中国女性面部光老化患者。所有患者每 4 周治疗一次，共治疗 3 次。在每次治疗前评估面部光老化的客观指标和患者满意度，并记录每次治疗后的疼痛评分和不良反应。
与基线相比，患者的所有面部光老化指标均有显著差异（p<0.01）。接受 3 次治疗后，色素指数降低 20.1%，红斑指数降低 23.9%，纹理指数降低 34.5%，细纹指数降低 28.4%，毛孔指数降低 56%，弹性 R2 升高 9.3%，F4 降低 17.1%，皮脂含量降低 55%。3 次治疗的平均满意度评分为 4.67（3.33，5.00），平均视觉模拟评分（VAS）疼痛评分为 7.00。治疗期间，治疗部位未出现炎症后色素沉着过度（PIH）、色素减退或水疱等严重不良反应。
皮秒倍频翠绿宝石激光联合长脉冲翠绿宝石激光治疗面部光老化疗效显著，患者满意度高，不良反应少。
