Department of Scientific Communication, Parfum Christian Dior, Neuilly sur Seine, France.
Dermatologist and President of the European LED Academy, La Farlede, France.
Skin Res Technol. 2023 Jul;29(7):e13391. doi: 10.1111/srt.13391.
Photobiomodulation is a process by which the absorption of red light energy produces a series of physiological effects at the cellular level such as the enhancement of mitochondrial Adenosine Triphosphate (ATP) production, cell signaling and growth factor synthesis, and the reduction of oxidative stress. Light emitting diodes (LEDs) photobiomodulation is an increasingly popular therapy for treating skin problems, especially for reversing the signs of skin aging.
The objective of this study is to demonstrate the effectiveness of a photobiomodulation treatment using red LEDs on the facial skin at a rate of two sessions per week for 3 months. The LED mask used is the Skin Light Dior x Lucibel mask diffusing a cold red light with a wavelength of 630 ± 10 nm and a power of 15.6 J/cm for a duration of 12 min.
In order to demonstrate the effectiveness of the mask in reversing the signs of skin aging, a clinical study was conducted on 20 healthy Caucasian women: the antiwrinkle effect by measuring the depth of the crow's feet wrinkle, the relaxation of the oval of the face by clinical scoring, the firmness and elasticity of the skin by cutometric measurement, the density of the dermis by ultrasound analysis, the smoothness of the skin by measuring the roughness at the cheek, the homogeneity of the complexion by chromametric measurement, the diameter of the pores by macrophotographs and finally the sebo-regulating effect by measurement of the rate of sebum and quantification of the number of pores containing porphyrin in the subjects presenting a mixed to oily skin. The satisfaction of the volunteers was also evaluated at the end of the study via a self-questionnaire.
The efficacy results measured after 1, 2, and 3 months of use are progressive and confirm the interest of LED photobiomodulation to reverse the visible signs of skin aging. All the volunteers observed an overall improvement in skin quality.
All the results observed confirm the interest of using photobiomodulation to reverse the visible signs of aging. These results last for up to 1 month after stopping the use of the mask, which is a sign of lasting structural and functional rejuvenation of the skin.
光生物调节是一种过程，其中红光能量的吸收在细胞水平上产生一系列生理效应，例如增强线粒体三磷酸腺苷（ATP）的产生、细胞信号转导和生长因子合成，以及减少氧化应激。发光二极管（LED）光生物调节是一种越来越受欢迎的治疗皮肤问题的方法，特别是用于逆转皮肤老化的迹象。
本研究的目的是证明每周进行两次，每次 12 分钟，共 3 个月的红色 LED 光生物调节治疗对面部皮肤的有效性。使用的 LED 面膜是 Skin Light Dior x Lucibel 面膜，它发出波长为 630±10nm、功率为 15.6 J/cm 的冷红光。
为了证明面膜在逆转皮肤老化迹象方面的有效性，对 20 名健康的白种女性进行了一项临床研究：通过测量鱼尾纹的深度来评估抗皱效果，通过临床评分评估面部椭圆形的放松程度，通过皮肤测量仪评估皮肤的紧致度和弹性，通过超声分析评估真皮密度，通过测量脸颊粗糙度评估皮肤的光滑度，通过色度测量评估肤色的均匀度，通过宏观照片评估毛孔直径，最后通过测量皮脂率和量化含有卟啉的毛孔数量来评估皮脂调节效果。研究结束时，志愿者还通过自我问卷评估了他们的满意度。
使用 1、2 和 3 个月后的疗效测量结果是渐进的，证实了 LED 光生物调节逆转可见皮肤老化迹象的兴趣。所有志愿者都观察到皮肤质量的整体改善。
所有观察到的结果都证实了使用光生物调节来逆转皮肤老化的可见迹象的兴趣。这些结果在停止使用面膜后长达 1 个月内仍然存在，这是皮肤结构和功能持久年轻化的迹象。
