Zhang Junyi, Hao Jianxiong, Wang Jingyi, Li Huiying, Zhao Dandan
College of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang, China.
Crit Rev Food Sci Nutr. 2024 Oct 5:1-10. doi: 10.1080/10408398.2024.2409340.
(), a gram-positive foodborne pathogen that can easily cause listeriosis. It secretes extracellular polymers and forms biofilms that are highly resistant to disinfection methods, such as UV light and germicides, posing risks to food processing equipment and food quality. Dispersion of biofilm is the cycle of its formation in which the bacteria return to planktonic state and become susceptible to antimicrobials, the strategic manipulation of biofilm dispersion is thus heralded as a novel and promising approach for the effective control of biofilm-related infections. Compared to the traditional methods, it is more effective to start with the composition of biofilms, cut off the production of their constituent substances, and genetically reduce the probability of biofilm formation. Meanwhile, the dispersion of bacteria can be supplemented with exogenous substances, making long-term control possible. This paper provides a brief but comprehensive overview of the mechanisms of biofilms or cross-contamination and their resistance properties, and facilitates our understanding and control of the prevention and containment of biofilm contamination based on the biofilm's active and passive diffusion strategies. This work provides practical guidelines for the food industry to guard against the enduring threat to food safety due to biofilms.
（）是一种革兰氏阳性食源性病原体，极易引发李斯特菌病。它会分泌胞外聚合物并形成生物膜，这些生物膜对紫外线和杀菌剂等消毒方法具有高度抗性，给食品加工设备和食品质量带来风险。生物膜的分散是其形成周期的一部分，在此过程中细菌恢复为浮游状态并变得易受抗菌剂影响，因此对生物膜分散进行策略性操控被视为有效控制与生物膜相关感染的一种新颖且有前景的方法。与传统方法相比，从生物膜的组成入手，切断其组成物质的产生，并通过基因手段降低生物膜形成的概率更为有效。同时，可以通过添加外源物质促进细菌的分散，从而实现长期控制。本文简要而全面地概述了生物膜或交叉污染的机制及其抗性特性，并基于生物膜的主动和被动扩散策略，有助于我们理解和控制生物膜污染的预防与遏制。这项工作为食品行业防范生物膜对食品安全造成的持久威胁提供了实用指南。
